• 1490 Citations
  • 21 h-Index
1978 …2017
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Research Output 1978 2017

  • 1490 Citations
  • 21 h-Index
  • 88 Article
  • 1 Review article
2017
4 Citations (Scopus)

Signalling assemblies: The odds of symmetry

Maksay, G. & Marsh, J. A., Jun 15 2017, In : Biochemical Society Transactions. 45, 3, p. 599-611 13 p.

Research output: Contribution to journalReview article

Proteins
Cell signaling
Biological Phenomena
Transcription Factors
Pharmacology
2014
9 Citations (Scopus)

Asymmetric perturbations of signalling oligomers

Maksay, G. & Toke, O., 2014, In : Progress in Biophysics and Molecular Biology. 114, 3, p. 153-169 17 p.

Research output: Contribution to journalArticle

Acid Sensing Ion Channels
Chaperonins
Ligand-Gated Ion Channels
Ionotropic Glutamate Receptors
Proteins
2013
4 Citations (Scopus)

Asymmetric perturbation of pLGICs: Action!

Maksay, G., Jun 2013, In : Trends in Pharmacological Sciences. 34, 6, p. 299-300 2 p.

Research output: Contribution to journalArticle

Molecular Sequence Data
Molecular Docking Simulation
Ligand-Gated Ion Channels
Bacterial Proteins
Amino Acid Sequence
2011
21 Citations (Scopus)

Allostery in pharmacology: Thermodynamics, evolution and design

Maksay, G., Sep 2011, In : Progress in Biophysics and Molecular Biology. 106, 3, p. 463-473 11 p.

Research output: Contribution to journalArticle

Thermodynamics
Allosteric Regulation
Pharmacology
Cognitive Science
Ligand-Gated Ion Channels
2 Citations (Scopus)

Differential effects of two major neurosteroids on cerebellar and cortical GABAA receptor binding and function

Maksay, G. & Fodor, L., Jan 10 2011, In : European Journal of Pharmacology. 650, 1, p. 94-101 8 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Neurotransmitter Agents
Pregnanolone
GABA Agonists
Cerebellum
2009
16 Citations (Scopus)

Different binding modes of tropeines mediating inhibition and potentiation of α1 glycine receptors

Maksay, G., Laube, B., Schemm, R., Grudzinska, J., Drwal, M. & Betz, H., Jun 2009, In : Journal of Neurochemistry. 109, 6, p. 1725-1732 8 p.

Research output: Contribution to journalArticle

Nortropanes
Glycine Receptors
tropisetron
Binding Sites
Substitution reactions
6 Citations (Scopus)

Ligand-gated pentameric ion channels, from binding to gating

Maksay, G., 2009, In : Current Molecular Pharmacology. 2, 3, p. 253-262 10 p.

Research output: Contribution to journalArticle

Ligand-Gated Ion Channels
Acetylcholine
Ligands
Aminobutyrates
Receptors, Serotonin, 5-HT3
2 Citations (Scopus)

Synthesis of heteroaromatic tropeines and heterogeneous binding to glycine receptors

Maksay, G., Vincze, Z. & Nemes, P., Oct 1 2009, In : Bioorganic and Medicinal Chemistry. 17, 19, p. 6872-6878 7 p.

Research output: Contribution to journalArticle

Glycine Receptors
Inhibitory Concentration 50
Esters
Receptors, Serotonin, 5-HT3
Strychnine
2008
6 Citations (Scopus)
Glycine Receptors
Strychnine
Propofol
Glycine
Mutation
4 Citations (Scopus)

Synthesis and receptor binding of new thieno[2,3-d]-pyrimidines as selective ligands of 5-HT3 receptors

Modica, M. N., Romeo, G., Salerno, L., Pittalà, V., Siracusa, M. A., Mereghetti, I., Cagnotto, A., Mennini, T., Gáspár, R., Gál, A., Falkay, G., Palkó, M., Maksay, G. & Fülöp, F., Jun 2008, In : Archiv der Pharmazie. 341, 6, p. 333-343 11 p.

Research output: Contribution to journalArticle

Receptors, Serotonin, 5-HT3
Receptors, Serotonin, 5-HT4
Ligands
Derivatives
Serotonin
7 Citations (Scopus)

Synthesis of (nor)tropeine (di)esters and allosteric modulation of glycine receptor binding

Maksay, G., Nemes, P., Vincze, Z. & Bíró, T., Feb 15 2008, In : Bioorganic and Medicinal Chemistry. 16, 4, p. 2086-2092 7 p.

Research output: Contribution to journalArticle

Glycine Receptors
Esters
Modulation
Strychnine
Glycine
2007
4 Citations (Scopus)

A 17β-derivative of allopregnanolone is a neurosteroid antagonist at a cerebellar subpopulation of GABA A receptors with nanomolar affinity

Maksay, G., Fodor, L., Bíró, T., Avlonitis, N. & Calogeropoulou, T., Aug 2007, In : British Journal of Pharmacology. 151, 7, p. 1078-1086 9 p.

Research output: Contribution to journalArticle

Pregnanolone
GABA-A Receptors
Neurotransmitter Agents
gamma-Aminobutyric Acid
Furosemide
2006
6 Citations (Scopus)

Allosteric modulation of [3H]EBOB binding to GABAA receptors by diflunisal analogues

Uusi-Oukari, M. & Maksay, G., Dec 2006, In : Neurochemistry International. 49, 7, p. 676-682 7 p.

Research output: Contribution to journalArticle

Diflunisal
GABA-A Receptors
gamma-Aminobutyric Acid
Fenamates
Synaptic Membranes
12 Citations (Scopus)

Expression of heteromeric glycine receptor-channels in rat spinal cultures and inhibition by neuroactive steroids

Fodor, L., Boros, A., Dezso, P. & Maksay, G., Nov 2006, In : Neurochemistry International. 49, 6, p. 577-583 7 p.

Research output: Contribution to journalArticle

Glycine Receptors
tropisetron
Steroids
Spinal Cord
Strychnine
31 Citations (Scopus)

Interactions of granisetron with an agonist-free 5-HT3A receptor model

Joshi, P. R., Suryanarayanan, A., Hazai, E., Schulte, M. K., Maksay, G. & Bikádi, Z., Jan 31 2006, In : Biochemistry. 45, 4, p. 1099-1105 7 p.

Research output: Contribution to journalArticle

Granisetron
Mutation
Nicotinic Receptors
Phenylalanine
Alanine
2005
9 Citations (Scopus)

Activation of ionotropic receptors and thermodynamics of binding

Maksay, G., Mar 2005, In : Neurochemistry International. 46, 4, p. 281-291 11 p.

Research output: Contribution to journalArticle

Cysteine Loop Ligand-Gated Ion Channel Receptors
Entropy
Thermodynamics
Aminobutyrates
Ionophores
7 Citations (Scopus)

Allosteric modulation of 5-HT3 serotonin receptors

Maksay, G., Bíró, T. & Bugovics, G., May 2 2005, In : European Journal of Pharmacology. 514, 1, p. 17-24 8 p.

Research output: Contribution to journalArticle

Granisetron
Receptors, Serotonin, 5-HT3
Serotonin
Prosencephalon
Serotonin Agents
8 Citations (Scopus)

High affinity, heterogeneous displacement of [3H]EBOB binding to cerebellar GABAA receptors by neurosteroids and GABA agonists

Maksay, G. & Bíró, T., Sep 2005, In : Neuropharmacology. 49, 4, p. 431-438 8 p.

Research output: Contribution to journalArticle

GABA-A Receptor Agonists
GABA Agonists
Neurotransmitter Agents
gamma-Aminobutyric Acid
GABA-A Receptors
16 Citations (Scopus)

Nanomolar allopregnanolone potentiates rat cerebellar GABAA receptors

Fodor, L., Bíró, T. & Maksay, G., Jul 22 2005, In : Neuroscience Letters. 383, 1-2, p. 127-130 4 p.

Research output: Contribution to journalArticle

Pregnanolone
GABA-A Receptors
gamma-Aminobutyric Acid
Inhibitory Concentration 50
Aminobutyrates
22 Citations (Scopus)

Novel 17β-substituted conformationally constrained neurosteroids that modulate GABAA receptors

Souli, C., Avlonitis, N., Calogeropoulou, T., Tsotinis, A., Maksay, G., Bíró, T., Politi, A., Mavromoustakos, T., Makriyannis, A., Reis, H. & Papadopoulos, M., Aug 11 2005, In : Journal of Medicinal Chemistry. 48, 16, p. 5203-5214 12 p.

Research output: Contribution to journalArticle

GABA-A Receptors
Neurotransmitter Agents
Pregnanolone
Steroids
Glycine Receptors
2004
7 Citations (Scopus)

Allosteric modulation of glycine receptors is more efficacious for partial rather than full agonists

Bíró, T. & Maksay, G., Jun 2004, In : Neurochemistry International. 44, 7, p. 521-527 7 p.

Research output: Contribution to journalArticle

Glycine Receptors
Strychnine
Taurine
Propofol
Glycine
7 Citations (Scopus)

Subunit rotation models activation of serotonin 5-HT3AB receptors by agonists

Maksay, G., Simonyi, M. & Bikádi, Z., Oct 2004, In : Journal of Computer-Aided Molecular Design. 18, 10, p. 651-664 14 p.

Research output: Contribution to journalArticle

serotonin
Chemical activation
activation
Ammonium Compounds
vestibules
12 Citations (Scopus)

Synthesis of tropeines and allosteric modulation of ionotropic glycine receptors

Maksay, G., Nemes, P. & Biró, T., Dec 2 2004, In : Journal of Medicinal Chemistry. 47, 25, p. 6384-6391 8 p.

Research output: Contribution to journalArticle

Glycine Receptors
Receptors, Serotonin, 5-HT3
Strychnine
Modulation
Glycine
3 Citations (Scopus)

Vinburnine decelerates [3H]N-methylscopolamine binding to recombinant human muscarinic M1-M4 acetylcholine receptors

Maksay, G., Bíró, T. & Kiss, B., Jan 12 2004, In : European Journal of Pharmacology. 483, 2-3, p. 229-232 4 p.

Research output: Contribution to journalArticle

N-Methylscopolamine
Cholinergic Receptors
Cholinergic Agents
Muscarinic M1 Receptors
Muscarinic M4 Receptors
2003
43 Citations (Scopus)

Binding Interactions of Antagonists with 5-Hydroxytryptamine3A Receptor Models

Maksay, G., Bikádi, Z. & Simonyi, M., 2003, In : Journal of Receptors and Signal Transduction. 23, 2-3, p. 255-270 16 p.

Research output: Contribution to journalArticle

tropisetron
Tubocurarine
Guinea Pigs
Granisetron
Serotonin 5-HT3 Receptor Antagonists
Neuropharmacology
Glycine Receptors
40 Citations (Scopus)

The pharmacology of spontaneously open α1β3ε GABAA receptor-ionophores

Maksay, G., Thompson, S. A. & Wafford, K. A., Jun 2003, In : Neuropharmacology. 44, 8, p. 994-1002 9 p.

Research output: Contribution to journalArticle

GABA-A Receptor Agonists
Ionophores
GABA-A Receptors
Neurotransmitter Agents
GABA Modulators
2002
15 Citations (Scopus)

Dual cooperative allosteric modulation of binding to ionotropic glycine receptors

Maksay, G. & Bíró, T., Dec 2002, In : Neuropharmacology. 43, 7, p. 1087-1098 12 p.

Research output: Contribution to journalArticle

Glycine Receptors
Nitrendipine
tropisetron
Glycine
Strychnine
9 Citations (Scopus)

Hyperekplexia mutation of glycine receptors: Decreased gating efficacy with altered binding thermodynamics

Maksay, G., Bíró, T. & Laube, B., Jul 15 2002, In : Biochemical Pharmacology. 64, 2, p. 285-288 4 p.

Research output: Contribution to journalArticle

Glycine Receptors
Thermodynamics
Mutation
Strychnine
Taurine
197 Citations (Scopus)

Modulation of glycine receptor function: A novel approach for therapeutic intervention at inhibitory synapses?

Laube, B., Maksay, G., Schemm, R. & Betz, H., Nov 1 2002, In : Trends in Pharmacological Sciences. 23, 11, p. 519-527 9 p.

Research output: Contribution to journalArticle

Glycine Receptors
Synapses
Protein Isoforms
Modulation
Molecular Models
2001
3 Citations (Scopus)

Bicarbonate and thiocyanate ions affect the gating of γ-aminobutyric acidA receptors in cultured rat cortical cells

Maksay, G., Fodor, L., Bielik, N. & Tarnawa, I., Oct 5 2001, In : Neuroscience Letters. 311, 3, p. 169-172 4 p.

Research output: Contribution to journalArticle

GABA-A Receptor Agonists
GABA-A Receptor Antagonists
Muscimol
Electrophysiology
Ionophores
4 Citations (Scopus)

Entropy as the predominant driving force of binding to human recombinant αxβ3γ2 GABAA receptors

Maksay, G. & McKernan, R., 2001, In : European Journal of Pharmacology. 411, 1-2, p. 55-60 6 p.

Research output: Contribution to journalArticle

Muscimol
Entropy
GABA-A Receptors
GABA-A Receptor Antagonists
Bromides
57 Citations (Scopus)

Subunit-specific modulation of glycine receptors by neurosteroids

Maksay, G., Laube, B. & Betz, H., 2001, In : Neuropharmacology. 41, 3, p. 369-376 8 p.

Research output: Contribution to journalArticle

Glycine Receptors
Neurotransmitter Agents
Dehydroepiandrosterone
Pregnenes
Dehydroepiandrosterone Sulfate
2000
31 Citations (Scopus)

Allosteric modulators affect the efficacy of partial agonists for recombinant GABA(A) receptors

Maksay, G., Thompson, S. A. & Wafford, K. A., 2000, In : British Journal of Pharmacology. 129, 8, p. 1794-1800 7 p.

Research output: Contribution to journalArticle

GABA-A Receptor Agonists
Chlordiazepoxide
GABA-A Receptors
Benzodiazepines
Pregnanolone
1999
30 Citations (Scopus)

Selective blocking effects of tropisetron and atropine on recombinant glycine receptors

Maksay, G., Laube, B. & Betz, H., 1999, In : Journal of Neurochemistry. 73, 2, p. 802-806 5 p.

Research output: Contribution to journalArticle

tropisetron
Glycine Receptors
Atropine
Glycine
Electrophysiology
1998
29 Citations (Scopus)
Glycine Receptors
Receptors, Serotonin, 5-HT3
Strychnine
Glycine
Ligands
18 Citations (Scopus)

Bimodal action of furosemide on convulsant [3H]EBOB binding to cerebellar and cortical GABA(A) receptors

Maksay, G., Finland, Korpi, E. R. & Uusi-Oukari, M., Oct 1 1998, In : Neurochemistry International. 33, 4, p. 353-358 6 p.

Research output: Contribution to journalArticle

Convulsants
Furosemide
GABA-A Receptors
Cerebellum
gamma-Aminobutyric Acid
8 Citations (Scopus)
Aminobutyrates
Ionophores
Thermodynamics
Temperature
GABA-A Receptors
1996
23 Citations (Scopus)
Serotonin 5-HT3 Receptor Agonists
Granisetron
Serotonin 5-HT3 Receptor Antagonists
tropisetron
Thermodynamics
28 Citations (Scopus)

From kinetics and thermodynamics of GABAA receptor binding to ionophore function.

Maksay, G., Oct 1996, In : Neurochemistry International. 29, 4, p. 361-370 10 p.

Research output: Contribution to journalArticle

Convulsants
Ionophores
GABA-A Receptors
Thermodynamics
Benzodiazepines
8 Citations (Scopus)
Convulsants
Stereoisomerism
Ionophores
Thermodynamics
Inhibitory Concentration 50
1995
8 Citations (Scopus)

Diazepam biphasically modulates [3h]TBOB binding to the convulsant site of the GABAa receptor complex

van Rijn, C. M., Dirksen, R., Bree, E. W. V. & Maksay, G., 1995, In : Journal of Receptors and Signal Transduction. 15, 6, p. 787-800 14 p.

Research output: Contribution to journalArticle

Convulsants
Diazepam
gamma-Aminobutyric Acid
Inhibitory Concentration 50
GABA Antagonists
1994
13 Citations (Scopus)

Common modes of action of γ-butyrolactones and pentylenetetrazol on the GABAA receptor-ionophore complex

Maksay, G., Molnár, P. & Gruber, L., Dec 15 1994, In : European Journal of Pharmacology: Molecular Pharmacology. 288, 1, p. 61-68 8 p.

Research output: Contribution to journalArticle

Pentylenetetrazole
Ionophores
GABA-A Receptors
Inhibitory Concentration 50
Convulsants
46 Citations (Scopus)

Thermodynamics of γ-aminobutyric acid type A receptor binding differentiate agonists from antagonists

Maksay, G., Aug 1994, In : Molecular Pharmacology. 46, 2, p. 386-390 5 p.

Research output: Contribution to journalArticle

Aminobutyrates
Thermodynamics
GABA-A Receptor Agonists
GABA-A Receptor Antagonists
RU 5135
1993
Convulsants
GABA-A Receptors
Anions
Arginine
Phenylglyoxal
16 Citations (Scopus)

Interconvertible kinetic states of t-butylbicycloorthobenzoate binding sites of the γ-aminobutyric acidA ionophores

Maksay, G. & Van Rijn, C. M., Dec 1993, In : Journal of Neurochemistry. 61, 6, p. 2081-2088 8 p.

Research output: Contribution to journalArticle

Ionophores
Binding Sites
Kinetics
gamma-Aminobutyric Acid
4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid
2 Citations (Scopus)
Glycine Receptors
Strychnine
Glycine
RU 5135
Alanine
8 Citations (Scopus)
GABA-A Receptors
Carbolines
ZK 91296
Ligands
Flunitrazepam
1992
5 Citations (Scopus)
Diethyl Pyrocarbonate
GABA-A Receptors
Diazepam
Histidine
Diacetyl
1991
15 Citations (Scopus)
Stereoisomerism
GABA-A Receptors
Diazepam
Oxazepam
gamma-Aminobutyric Acid