• 514 Citations
  • 13 h-Index
20072019

Research output per year

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Research Output

  • 514 Citations
  • 13 h-Index
  • 35 Article
  • 3 Review article
  • 1 Comment/debate
2019

4th ESPT Conference: Pharmacogenomics and personalized medicine - Research progress and clinical implementation

Sipeky, C., Llerena, A., Manolopoulos, V. G., Pearson, E., Mlakar, V., Gozzo, L., Simmaco, M., Marchetti, P., Re, M. D., Stankovic, S., Meyer, U., Cascorbi, I., Ingelman-Sundberg, M., Suarez-Kurtz, G., Marc, J., Katsila, T., Paulmichl, M., Nofziger, C., Ansari, M., Drago, F. & 1 others, Van Schaik, R. H. N., Jan 1 2019, In : Pharmacogenomics. 20, 15, p. 1063-1069 7 p.

Research output: Contribution to journalArticle

4th ESPT summer school: Precision medicine and personalised health

Mlakar, V., Marc, J., Manolopoulos, V. G., Cascorbi, I., Stanković, S., Llerena, A., Simmaco, M., Visvikis-Siest, S., Amstutz, U., Sipeky, C., Meyer, U. A., Meier-Abt, P., Van Schaik, R. H. & Ansari, M., May 24 2019, In : Pharmacogenomics. 20, 7, p. 471-474 4 p.

Research output: Contribution to journalArticle

PARP inhibitors in prostate cancer—The preclinical rationale and current clinical development

Virtanen, V., Paunu, K., Ahlskog, J. K., Varnai, R., Sipeky, C. & Sundvall, M., Aug 1 2019, In : Genes. 10, 8, 565.

Research output: Contribution to journalReview article

Open Access

Pharmacogenomic biomarkers in docetaxel treatment of prostate cancer: From discovery to implementation

Varnai, R., Koskinen, L. M., Mäntylä, L. E., Szabo, I., Fitzgerald, L. M. & Sipeky, C., Aug 1 2019, In : Genes. 10, 8, 599.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)

Risk Prediction of Prostate Cancer with Single Nucleotide Polymorphisms and Prostate Specific Antigen

Li-Sheng Chen, S., Ching-Yuan Fann, J., Sipeky, C., Yang, T. K., Yueh-Hsia Chiu, S., Ming-Fang Yen, A., Laitinen, V., Tammela, T. L. J., Stenman, U. H., Auvinen, A., Schleutker, J. & Chen, H. H., Mar 1 2019, In : The Journal of urology. 201, 3, p. 486-495 10 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

ANO7 is associated with aggressive prostate cancer

PRACTICAL Consortium, Jan 1 2018, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Biology and Clinical Implications of the 19q13 Aggressive Prostate Cancer Susceptibility Locus

The PRACTICAL Consortium, Jan 1 2018, (Accepted/In press) In : Cell.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Germline variants in IL4, MGMT and AKT1 are associated with prostate cancer-specific mortality: An analysis of 12,082 prostate cancer cases

FitzGerald, L. M., Zhao, S., Leonardson, A., Geybels, M. S., Kolb, S., Lin, D. W., Wright, J. L., Eeles, R., Kote-Jarai, Z., Govindasami, K., Giles, G. G., Southey, M. C., Schleutker, J., Tammela, T. L., Sipeky, C., Penney, K. L., Stampfer, M. J., Gronberg, H., Wiklund, F., Stattin, P. & 5 others, Hugosson, J., Karyadi, D. M., Ostrander, E. A., Feng, Z. & Stanford, J. L., Jan 3 2018, (Accepted/In press) In : Prostate Cancer and Prostatic Diseases. p. 1-10 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Personalized laboratory medicine: A patient-centered future approach

Prodan Žitnik, I., Černe, D., Mancini, I., Simi, L., Pazzagli, M., Di Resta, C., Podgornik, H., Repič Lampret, B., Trebušak Podkrajšek, K., Sipeky, C., Van Schaik, R., Brandslund, I., Vermeersch, P., Schwab, M. & Marc, J., Jul 10 2018, (Accepted/In press) In : Clinical Chemistry and Laboratory Medicine.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Synergistic interaction of HOXB13 and CIP2A predisposes to aggressive prostate cancer

Sipeky, C., Gao, P., Zhang, Q., Wang, L., Ettala, O., Talala, K. M., Tammela, T. L. J., Auvinen, A., Wiklund, F., Wei, G. H. & Schleutker, J., Dec 15 2018, In : Clinical Cancer Research. 24, 24, p. 6265-6276 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2017

CYP2C9 and VKORC1 in therapeutic dosing and safety of acenocoumarol treatment: implication for clinical practice in Hungary

Varnai, R., Sipeky, C., Nagy, L., Balogh, S. & Melegh, B., Dec 1 2017, In : Environmental Toxicology and Pharmacology. 56, p. 282-289 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Genetic association analysis of the RTK/ERK pathway with aggressive prostate cancer highlights the potential role of CCND2 in disease progression

Chen, Y., Zhang, Q., Wang, Q., Li, J., Sipeky, C., Xia, J., Gao, P., Hu, Y., Zhang, H., Yang, X., Chen, H., Jiang, Y., Yang, Y., Yao, Z., Chen, Y., Gao, Y., Tan, A., Liao, M., Schleutker, J., Xu, J. & 3 others, Sun, Y., Wei, G. H. & Mo, Z., Dec 1 2017, In : Scientific Reports. 7, 1, 4538.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Genome-wide association study of prostate cancer-specific survival

Szulkin, R., Karlsson, R., Whitington, T., Aly, M., Gronberg, H., Eeles, R. A., Easton, D. F., Kote-Jarai, Z., Al Olama, A. A., Benlloch, S., Muir, K., Giles, G. G., Southey, M. C., Fitzgerald, L. M., Henderson, B. E., Schumacher, F. R., Haiman, C. A., Sipeky, C., Tammela, T. J., Nordestgaard, B. G. & 62 others, Key, T. J., Travis, R. C., Neal, D. E., Donovan, J. L., Hamdy, F. C., Pharoah, P. D. P., Pashayan, N., Khaw, K. T., Stanford, J. L., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Maier, C., Vogel, W., Luedeke, M., Herkommer, K., Kibel, A. S., Cybulski, C., Lubinski, J., Kluzniak, W., Cannon-Albright, L., Brenner, H., Herrmann, V., Holleczek, B., Park, J. Y., Sellers, T. A., Lim, H. Y., Slavov, C., Kaneva, R. P., Mitev, V. I., Spurdle, A., Teixeira, M. R., Paulo, P., Maia, S., Pandha, H., Michael, A., Kierzek, A., Batra, J., Clements, J. A., Albanes, D., Andriole, G. L., Berndt, S. I., Chanock, S., Gapstur, S. M., Giovannucci, E. L., Hunter, D. J., Kraft, P., Le Marchand, L., Ma, J., Mondul, A. M., Penney, K. L., Stampfer, M. J., Stevens, V. L., Weinstein, S. J., Trichopoulou, A., Bueno-De-mesquita, B. H., Tjønneland, A., Cox, D. G., Maehle, L., Schleutker, J., Lindstrom, S. & Wiklund, F., Nov 2015, In : Cancer Epidemiology Biomarkers and Prevention. 24, 11, p. 1796-1800 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Interethnic variability of CYP4F2 (V433M) in admixed population of Roma and Hungarians

Sipeky, C., Weber, A., Melegh, B. I., Matyas, P., Janicsek, I., Szalai, R., Szabo, I., Varnai, R., Tarlos, G., Ganczer, A. & Melegh, B., Jul 1 2015, In : Environmental Toxicology and Pharmacology. 40, 1, p. 280-283 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Marked differences in frequencies of statin therapy relevant SLCO1B1 variants and haplotypes between Roma and Hungarian populations

Nagy, A., Sipeky, C., Szalai, R., Melegh, B. I., Matyas, P., Ganczer, A., Toth, K. & Melegh, B., Sep 3 2015, In : BMC genetics. 16, 1, 108.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Significant interethnic differencies in functional variants of PON1 and P2RY12 genes in Roma and Hungarian population samples

Janicsek, I., Sipeky, C., Bene, J., Duga, B., Melegh, B., Sümegi, K., Jaromi, L., Magyari, L. & Melegh, B., Jan 1 2015, In : Molecular Biology Reports. 42, 1, p. 227-232 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2014

Lower carrier rate of GJB2 W24X ancestral Indian mutation in Roma samples from Hungary: Implication for public health intervention

Sipeky, C., Matyas, P., Melegh, M., Janicsek, I., Szalai, R., Szabo, I., Varnai, R., Tarlos, G., Ganczer, A. & Melegh, B., Sep 2014, In : Molecular Biology Reports. 41, 9, p. 6105-6110 6 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2013

High prevalence of CYP2C19*2 allele in Roma samples: Study on Roma and Hungarian population samples with review of the literature

Sipeky, C., Weber, A., Szabo, M., Melegh, B. I., Janicsek, I., Tarlos, G., Szabo, I. & Sumegi, K., Aug 1 2013, In : Molecular Biology Reports. 40, 8, p. 4727-4735 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2012

Thiopurin s-metil-transzferáz gén vizsgálatának jelentosége egy eset kapcsán

Translated title of the contribution: Importance of thiopurine s-methyltransferase gene testSipeky, C., Maász, A., Tarlós, G., Komlósi, K., Éva, P. & Melegh, B., Feb 1 2012, In : Orvosi hetilap. 153, 5, p. 191-194 4 p.

Research output: Contribution to journalArticle

2011
30 Citations (Scopus)

Interaction between CTLA4 gene and IBD5 locus in Hungarian Crohn's disease patients

Csöngei, V., Járomi, L., Sáfrány, E., Sipeky, C., Magyari, L., Polgár, N., Bene, J., Sarlós, P., Lakner, L., Baricza, E., Szabó, M., Rappai, G. & Melegh, B., Sep 1 2011, In : International Journal of Colorectal Disease. 26, 9, p. 1119-1125 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
15 Citations (Scopus)

Triglyceride level-influencing functional variants of the ANGPTL3, CILP2, and TRIB1 loci in ischemic stroke

Járomi, L., Csöngei, V., Polgár, N., Rappai, G., Szolnoki, Z., Maász, A., Horvatovich, K., Sáfrány, E., Sipeky, C., Magyari, L. & Melegh, B., Sep 1 2011, In : NeuroMolecular Medicine. 13, 3, p. 179-186 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2010

Functional variants of glucokinase regulatory protein and apolipoprotein A5 genes in ischemic stroke

Járomi, L., Csöngei, V., Polgár, N., Szolnoki, Z., Maász, A., Horvatovich, K., Faragó, B., Sipeky, C., Sáfrány, E., Magyari, L., Kisfali, P., Mohás, M., Janicsek, I., Lakner, L. & Melegh, B., May 2010, In : Journal of Molecular Neuroscience. 41, 1, p. 121-128 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Interaction of the major inflammatory bowel disease susceptibility alleles in Crohn's disease patients

Csöngei, V., Járomi, L., Sáfrány, E., Sipeky, C., Magyari, L., Faragó, B., Bene, J., Polgár, N., Lakner, L., Sarlós, P., Varga, M. & Melegh, B., Jan 14 2010, In : World journal of gastroenterology. 16, 2, p. 176-183 8 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Interleukin-23 receptor gene variants in Hungarian systemic lupus erythematosus patients

Safrany, E., Hobor, R., Jakab, L., Tarr, T., Csongei, V., Jaromi, L., Sipeky, C., Valasek, A., Zeher, M., Fust, G., Czirjak, L. & Melegh, B., Feb 1 2010, In : Inflammation Research. 59, 2, p. 159-164 6 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
17 Citations (Scopus)
2009

Az 5q31 IBD5-régióban található IGR és SLC22A4/SLC22A5 variánsok lehetséges szerepe a gyulladásos bélbetegség kialakulásában

Translated title of the contribution: Possible role of selected IGR and SLC22A4/SLC22A5 loci in development of infl ammatory bowel diseasesLakner, L., Csöngei, V., Magyari, L., Varga, M., Miheller, P., Sarlós, P., Orosz, P., Bári, Z., Takács, I., Járomi, L., Sáfrány, E., Sipeky, C., Bene, J., Tulassay, Z., Döbrönte, Z. & Melegh, B., Jul 1 2009, In : Orvosi hetilap. 150, 29, p. 1375-1380 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Interethnic differences of CYP2C9 alleles in healthy Hungarian and Roma population samples: Relationship to worldwide allelic frequencies

Sipeky, C., Lakner, L., Szabo, M., Takacs, I., Tamasi, V., Polgar, N., Falus, A. & Melegh, B., Nov 1 2009, In : Blood Cells, Molecules, and Diseases. 43, 3, p. 239-242 4 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
51 Citations (Scopus)

Vitamin K epoxide reductase complex 1 (VKORC1) haplotypes in healthy Hungarian and Roma population samples

Sipeky, C., Csongei, V., Jaromi, L., Safrany, E., Polgar, N., Lakner, L., Szabol, M., Takacs, I. & Melegh, B., Aug 27 2009, In : Pharmacogenomics. 10, 6, p. 1026-1032 7 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2008

Apolipoprotein A5 gene IVS3+G476A allelic variant confers susceptibility for development of ischemic stroke

Maasz, A., Kisfali, P., Jaromi, L., Horvatovich, K., Szolnoki, Z., Csongei, V., Safrany, E., Sipeky, C., Hadarits, F. & Melegh, B., Jul 15 2008, In : Circulation Journal. 72, 7, p. 1065-1070 6 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
92 Citations (Scopus)

K-vitamin-epoxidreduktź gén haplocsoport-meghatározása: Egy újabb elem az antikoaguláns terápia optimalizálásában

Translated title of the contribution: Haplogroup analysis of vitamin-K epoxide reductase (VKORC1) gene: Novel element in the optimization of anticoagulant therapySipeky, C. & Melegh, B., Sep 28 2008, In : Orvosi hetilap. 149, 39, p. 1839-1844 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2007

A mitokondriális DNS és mutációi: Újabb ismeretek egy új területen

Translated title of the contribution: Mitochondrial DNA and its mutations: Novel fields in a new eraSáfrány, E., Csöngei, V., Járomi, L., Maász, A., Magyari, L., Sipeky, C. & Melegh, B., May 27 2007, In : Orvosi hetilap. 148, 21, p. 971-978 8 p.

Research output: Contribution to journalReview article

Apolipoprotein A5 T-1131C variant confers risk for metabolic syndrome

Maász, A., Kisfali, P., Horvatovich, K., Mohás, M., Markó, L., Csöngei, V., Faragó, B., Járomi, L., Magyari, L., Sáfrány, E., Sipeky, C., Wittmann, I. & Melegh, B., Jan 1 2007, In : Pathology and Oncology Research. 13, 3, p. 243-247 5 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
8 Citations (Scopus)