• 3534 Citations
  • 26 h-Index
1993 …2019

Research output per year

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Research Output

2019

Glomerular collagen deposition and lipocalin-2 expression are early signs of renal injury in prediabetic obese rats

Bukosza, E. N., Kaucsár, T., Godó, M., Lajtár, E., Tod, P., Koncsos, G., Varga, Z. V., Baranyai, T., Tu, N. M., Schachner, H., Sőti, C., Ferdinandy, P., Giricz, Z., Szénási, G. & Hamar, P., Sep 1 2019, In : International journal of molecular sciences. 20, 17, 4266.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2018

DAF-21/Hsp90 is required for C. elegans longevity by ensuring DAF-16/FOXO isoform A function

Somogyvári, M., Gecse, E. & Söti, C., Dec 1 2018, In : Scientific Reports. 8, 1, 12048.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Hsp90 stabilizes SIRT1 orthologs in mammalian cells and C. elegans

Nguyen, M. T., Somogyvári, M. & Sőti, C., Nov 20 2018, In : International journal of molecular sciences. 19, 11, 3661.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2015

Distinct roles of the RasGAP family proteins in C. elegans associative learning and memory

Gyurkó, M. D., Csermely, P., Soti, C. & Steták, A., Oct 15 2015, In : Scientific reports. 5, 15084.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Multitarget network strategies to influence memory and forgetting: The Ras/Mapk pathway as a novel option

Dávid Gyurkó, M., Steták, A., Sőti, C. & Csermely, P., May 1 2015, In : Mini-Reviews in Medicinal Chemistry. 15, 8, p. 696-704 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2014

LPS-induced delayed preconditioning is mediated by Hsp90 and involves the heat shock response in mouse kidney

Kaucsár, T., Bodor, C., Godó, M., Szalay, C., Révész, C., Németh, Z., Mózes, M., Szénási, G., Rosivall, L., Soti, C. & Hamar, P., Mar 19 2014, In : PloS one. 9, 3, e92004.

Research output: Contribution to journalArticle

6 Citations (Scopus)

System level mechanisms of adaptation, learning, memory formation and evolvability: The role of chaperone and other networks

Gyurkó, D. M., Soti, C., Steták, A. & Csermely, P., Jan 1 2014, In : Current Protein and Peptide Science. 15, 3, p. 171-188 18 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2012

A role for SKN-1/Nrf in pathogen resistance and immunosenescence in caenorhabditis elegans

Papp, D., Csermely, P. & Soti, C., Apr 2012, In : PLoS Pathogens. 8, 4, e1002673.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Misfolded proteins inhibit proliferation and promote stress-induced death in SV40-transformed mammalian cells

Arslan, M. A., Chikina, M., Csermely, P. & Soti, C., Feb 1 2012, In : FASEB Journal. 26, 2, p. 766-777 12 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

RNA interference links oxidative stress to the inhibition of heat stress adaptation

Spiró, Z., Arslan, M. A., Somogyvári, M., Nguyen, M. T., Smolders, A., Dancsó, B., Németh, N., Elek, Z., Braeckman, B. P., Csermely, P. & Soti, C., Sep 15 2012, In : Antioxidants and Redox Signaling. 17, 6, p. 890-901 12 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)
2011

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

Burnett, C., Valentini, S., Cabreiro, F., Goss, M., Somogyvári, M., Piper, M. D., Hoddinott, M., Sutphin, G. L., Leko, V., McElwee, J. J., Vazquez-Manrique, R. P., Orfila, A. M., Ackerman, D., Au, C., Vinti, G., Riesen, M., Howard, K., Neri, C., Bedalov, A., Kaeberlein, M. & 3 others, Söti, C., Partridge, L. & Gems, D., Sep 22 2011, In : Nature. 477, 7365, p. 482-485 4 p.

Research output: Contribution to journalArticle

439 Citations (Scopus)

Low ambient temperature reveals distinct mechanisms for MDMA-induced serotonergic toxicity and astroglial Hsp27 heat shock response in rat brain

Ádori, C., Andó, R. D., Balázsa, T., Sti, C., Vas, S., Palkovits, M., Kovács, G. G. & Bagdy, G., Oct 1 2011, In : Neurochemistry international. 59, 5, p. 695-705 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2010

The heat shock connection of metabolic stress and dietary restriction

Dancsó, B., Spiró, Z., Arslan, M. A., Nguyen, M. T., Papp, D., Csermely, P. & Söti, C., Feb 1 2010, In : Current Pharmaceutical Biotechnology. 11, 2, p. 139-145 7 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)
2009

Ageing as a price of cooperation and complexity: Self-organization of complex systems causes the gradual deterioration of constituent networks

Kiss, H. J. M., Mihalik, Á., Nánási, T., Ory, B., Spiró, Z., Soti, C. & Csermely, P., Jul 31 2009, In : BioEssays. 31, 6, p. 651-664 14 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2008

Expected functions of salivary HSP70 in the oral cavity (Review Article)

Fábián, T. K., Söti, C., Nguyen, M. T., Csermely, P. & Fejérdy, P., Mar 2008, Heat Shock Proteins: New Research. Nova Science Publishers, Inc., p. 321-340 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations (Scopus)
37 Citations (Scopus)

Resveratrol induces the heat-shock response and protects human cells from severe heat stress

Putics, Á., Végh, E. M., Csermely, P. & Soti, C., Jan 1 2008, In : Antioxidants and Redox Signaling. 10, 1, p. 65-75 11 p.

Research output: Contribution to journalArticle

67 Citations (Scopus)

Systems biology of molecular chaperone networks

Csermely, P., Korcsmáros, T., Kovács, I. A., Szalay, M. & Söti, C., May 20 2008, The Biology of Extracellular Molecular Chaperones. Wiley-Blackwell, p. 45-58 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Systems biology of molecular chaperone networks

Csermely, P., Korcsmáros, T., Kovács, I. A., Szalay, M. S. & Soti, C., Nov 18 2008, Biology of Extracellular Molecular Chaperones, The. p. 45-54 10 p. (Novartis Foundation Symposium; vol. 291).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Citations (Scopus)

Zinc, metallothioneins, longevity: Effect of zinc supplementation on antioxidant response: A zincage study

Mocchegiani, E., Malavolta, M., Giacconi, R., Cipriano, C., Costarelli, L., Muti, E., Tesei, S., Giuli, C., Papa, R., Marcellini, F., Mariani, E., Rink, L., Herbein, G., Fulop, T., Monti, D., Jajte, J., Dedoussis, G., Gonos, E. S., Buerkle, A., Friguet, B. & 7 others, Mecocci, P., Colasanti, M., Soti, C., Mazzatti, D., Blasco, M., Aspinall, R. & Pawelec, G., Apr 1 2008, In : Rejuvenation Research. 11, 2, p. 419-423 5 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Zinc supplementation boosts the stress response in the elderly: Hsp70 status is linked to zinc availability in peripheral lymphocytes

Putics, Á., Vödrös, D., Malavolta, M., Mocchegiani, E., Csermely, P. & Soti, C., May 1 2008, In : Experimental gerontology. 43, 5, p. 452-461 10 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
2007

Aging cellular networks: Chaperones as major participants

Soti, C. & Csermely, P., Jan 1 2007, In : Experimental gerontology. 42, 1-2, p. 113-119 7 p.

Research output: Contribution to journalReview article

50 Citations (Scopus)

Chaperones as parts of cellular networks

Csermely, P., Söti, C. & Blatch, G. L., Jan 1 2007, Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks. Springer New York, p. 55-63 9 p. (Advances in Experimental Medicine and Biology; vol. 594).

Research output: Chapter in Book/Report/Conference proceedingChapter

25 Citations (Scopus)

Chaperones as parts of cellular networks.

Csermely, P., Söti, C. & Blatch, G. L., 2007, In : Advances in Experimental Medicine and Biology. 594, p. 55-63 9 p.

Research output: Contribution to journalArticle

Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β generates sensitivity to the Hsp90 inhibitor radicicol

Millson, S. H., Truman, A. W., Rácz, A., Hu, B., Panaretou, B., Nuttall, J., Mollapour, M., Söti, C. & Piper, P. W., Sep 1 2007, In : FEBS Journal. 274, 17, p. 4453-4463 11 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Potential immunological functions of salivary Hsp70 in mucosal and periodontal defense mechanisms

Fábián, T. K., Fejérdy, P., Nguyen, M. T., Sőti, C. & Csermely, P., Apr 2007, In : Archivum Immunologiae et Therapiae Experimentalis. 55, 2, p. 91-98 8 p.

Research output: Contribution to journalReview article

36 Citations (Scopus)

Protein stress and stress proteins: Implications in aging and disease

Soti, C. & Csermely, P., Apr 1 2007, In : Journal of Biosciences. 32, 3, p. 511-515 5 p.

Research output: Contribution to journalReview article

47 Citations (Scopus)
2006

Cellular networks and the aging process

Csermely, P. & Soti, C., Apr 1 2006, In : Archives of Physiology and Biochemistry. 112, 2, p. 60-64 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Pharmacological modulation of the heat shock response

Soti, C. & Csermely, P., Dec 1 2006, Molecular Chaperones in Health and Disease. Gaestel, M. (ed.). p. 417-436 20 p. (Handbook of Experimental Pharmacology; vol. 172).

Research output: Chapter in Book/Report/Conference proceedingChapter

20 Citations (Scopus)

Protein homeostasis and molecular chaperones in aging.

Arslan, M. A., Csermely, P. & Sőti, C., Jan 1 2006, In : Biogerontology. 7, 5-6, p. 383-389 7 p.

Research output: Contribution to journalReview article

29 Citations (Scopus)
2005

Heat shock proteins as emerging therapeutic targets

Sõti, C., Nagy, E., Giricz, Z., Vígh, L., Csermely, P. & Ferdinandy, P., Nov 1 2005, In : British journal of pharmacology. 146, 6, p. 769-780 12 p.

Research output: Contribution to journalReview article

305 Citations (Scopus)

Modelling the actions of chaperones and their role in ageing

Proctor, C. J., Soti, C., Boys, R. J., Gillespie, C. S., Shanley, D. P., Wilkinson, D. J. & Kirkwood, T. B. L., Jan 1 2005, In : Mechanisms of Ageing and Development. 126, 1, p. 119-131 13 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Molecular chaperones as regulatory elements of cellular networks

Soti, C., Pál, C., Papp, B. & Csermely, P., Apr 2005, In : Current Opinion in Cell Biology. 17, 2, p. 210-215 6 p.

Research output: Contribution to journalReview article

83 Citations (Scopus)
2004

Inhibition of Hsp90: A new strategy for inhibiting protein kinases

Sreedhar, A. S., Soti, C. & Csermely, P., Mar 11 2004, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1697, 1-2, p. 233-242 10 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)
2003

Aging and molecular chaperones

Soti, C. & Csermely, P., Oct 2003, In : Experimental gerontology. 38, 10, p. 1037-1040 4 p.

Research output: Contribution to journalArticle

117 Citations (Scopus)

Apoptosis, necrosis and cellular senescence: chaperone occupancy as a potential switch.

Sõti, C., Sreedhar, A. S. & Csermely, P., Feb 2003, In : Aging cell. 2, 1, p. 39-45 7 p.

Research output: Contribution to journalReview article

76 Citations (Scopus)
60 Citations (Scopus)

Molecular chaperones, evolution and medicine

Csermely, P., Soti, C., Kalmar, E., Papp, E., Pato, B., Vermes, A. & Sreedhar, A. S., Dec 29 2003, In : Journal of Molecular Structure: THEOCHEM. 666-667, p. 373-380 8 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Molecular chaperones, stress proteins and redox homeostasis

Papp, E., Nardai, G., Soti, C. & Csermely, P., Jan 1 2003, In : BioFactors. 17, 1-4, p. 249-257 9 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)

Stresszfehérjék az orvostudományban.

Translated title of the contribution: Stress proteins in medicineSóti, C., Nardai, G. & Csermely, P., Mar 30 2003, In : Orvosi hetilap. 144, 13, p. 605-611 7 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

The Heat Shock Protein 90-Targeting Drug Cisplatin Selectively Inhibits Steroid Receptor Activation

Rosenhagen, M. C., Sõti, C., Schmidt, U., Wochnik, G. M., Hartl, F. U., Holsboer, F., Young, J. C. & Rein, T., Oct 1 2003, In : Molecular Endocrinology. 17, 10, p. 1991-2001 11 p.

Research output: Contribution to journalArticle

49 Citations (Scopus)
2002
181 Citations (Scopus)

Chaperone function and chaperone overload in the aged. A preliminary analysis

Nardai, G. Á., Csermely, P. & Söti, C., Oct 1 2002, In : Experimental gerontology. 37, 10-11, p. 1257-1262 6 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Chaperones and aging: Role in neurodegeneration and in other civilizational diseases

Söti, C. & Csermely, P., Dec 2002, In : Neurochemistry international. 41, 6, p. 383-389 7 p.

Research output: Contribution to journalShort survey

80 Citations (Scopus)

Chaperones come of age

Söti, C. & Csermely, P., Apr 1 2002, In : Cell Stress and Chaperones. 7, 2, p. 186-190 5 p.

Research output: Contribution to journalReview article

40 Citations (Scopus)
2000

Interaction of the human DnaJ homologue, HSJ1b with the 90 kDa heat shock protein, Hsp90

Schnaider, T., Soti, C., Cheetham, M. E., Miyata, Y., Yahara, I. & Csermely, P., Aug 11 2000, In : Life Sciences. 67, 12, p. 1455-1465 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Molecular chaperones and the aging process

Söti, C. & Csermely, P., Jan 1 2000, In : Biogerontology. 1, 3, p. 225-233 9 p.

Research output: Contribution to journalReview article

92 Citations (Scopus)
1998

Characterization of the nucleotide binding properties of the 90 kDa heat shock protein (Hsp90)

Sőti, C. & Csermely, P., Oct 1998, In : Journal of Biosciences. 23, 4, p. 347-352 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Interaction of vanadate oligomers and permolybdate with the 90-kDa heat-shock protein, Hsp90

Söti, C., Radics, L., Yahara, I. & Csermely, P., Aug 1 1998, In : European Journal of Biochemistry. 255, 3, p. 611-617 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Molecular chaperones in the etiology and therapy of cancer

Soti, C. & Csermely, P., Jan 1 1998, In : Pathology and Oncology Research. 4, 4, p. 316-321 6 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)