• 3629 Citations
  • 30 h-Index
19972019

Research output per year

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Research Output

2019

Guest Editorial

Chinopoulos, C. & Starkov, A., Oct 1 2019, In : Neurochemical research. 44, 10, p. 2237-2238 2 p.

Research output: Contribution to journalEditorial

Open Access

Mutated SUCLG1 causes mislocalization of SUCLG2 protein, morphological alterations of mitochondria and an early-onset severe neurometabolic disorder

Chinopoulos, C., Batzios, S., van den Heuvel, L. P., Rodenburg, R., Smeets, R., Waterham, H. R., Turkenburg, M., Ruiter, J. P., Wanders, R. J. A., Doczi, J., Horvath, G., Dobolyi, A., Vargiami, E., Wevers, R. A. & Zafeiriou, D., Jan 2019, In : Molecular Genetics and Metabolism. 126, 1, p. 43-52 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Response to “Leigh-like syndrome with mild mtDNA depletion due to the SUCLG1 variant c.626C>A”

Chinopoulos, C., Wevers, R. A., Waterham, H. R. & Zafeiriou, D., Mar 1 2019, In : Molecular Genetics and Metabolism Reports. 18, 1 p.

Research output: Contribution to journalLetter

Succinate in ischemia: Where does it come from?

Chinopoulos, C., Oct 2019, In : International Journal of Biochemistry and Cell Biology. 115, 105580.

Research output: Contribution to journalShort survey

3 Citations (Scopus)

The Effect of 2-Ketobutyrate on Mitochondrial Substrate-Level Phosphorylation

Bui, D., Ravasz, D. & Chinopoulos, C., Oct 1 2019, In : Neurochemical research. 44, 10, p. 2301-2306 6 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Therapeutic benefit of combining calorie-restricted ketogenic diet and glutamine targeting in late-stage experimental glioblastoma

Mukherjee, P., Augur, Z. M., Li, M., Hill, C., Greenwood, B., Domin, M. A., Kondakci, G., Narain, N. R., Kiebish, M. A., Bronson, R. T., Arismendi-Morillo, G., Chinopoulos, C. & Seyfried, T. N., Dec 1 2019, In : Communications Biology. 2, 1, 200.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)
2018

Ant1 mutant mice bridge the mitochondrial and serotonergic dysfunctions in bipolar disorder

Chinopoulos, C., Jan 1 2018, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost

Salin, K., Villasevil, E. M., Anderson, G. J., Auer, S. K., Selman, C., Hartley, R. C., Mullen, W., Chinopoulos, C. & Metcalfe, N. B., Sep 2018, In : Functional Ecology. 32, 9, p. 2149-2157 9 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin

Varjú, I., Farkas, V. J., Kőhidai, L., Szabó, L., Farkas, Á. Z., Polgár, L., Chinopoulos, C. & Kolev, K., Dec 1 2018, In : Scientific Reports. 8, 1, 5366.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Mitochondrial permeability transition pore: Back to the drawing board

Chinopoulos, C., Jul 2018, In : Neurochemistry international. 117, p. 49-54 6 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)

Mycoplasma infection and hypoxia initiate succinate accumulation and release in the VM-M3 cancer cells

Flores, R. E., Brown, A. K., Taus, L., Khoury, J., Glover, F., Kami, K., Sarangarajan, R., Walshe, T. E., Narain, N. R., Kiebish, M. A., Shelton, L. M., Chinopoulos, C. & Seyfried, T. N., Sep 2018, In : Biochimica et Biophysica Acta - Bioenergetics. 1859, 9, p. 975-983 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

OXPHOS Defects Due to mtDNA Mutations: Glutamine to the Rescue!

Chinopoulos, C., Jun 5 2018, In : Cell Metabolism. 27, 6, p. 1165-1167 3 p.

Research output: Contribution to journalShort survey

2 Citations (Scopus)

Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia-ANT

Chen, E., Kiebish, M. A., McDaniel, J., Niedzwiecka, K., Kucharczyk, R., Ravasz, D., Gao, F., Narain, N. R., Sarangarajan, R., Seyfried, T. N., Adam-Vizi, V. & Chinopoulos, C., Dec 1 2018, In : Scientific reports. 8, 1, 5915.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The RCR and ATP/O indices can give contradictory messages about mitochondrial efficiency

Salin, K., Villasevil, E. M., Anderson, G. J., Selman, C., Chinopoulos, C. & Metcalfe, N. B., 2018, In : Integrative and comparative biology. 58, 3, p. 486-494 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

ATP synthase complex and the mitochondrial permeability transition pore: Poles of attraction

Chinopoulos, C., Jul 2017, In : EMBO Reports. 18, 7, p. 1041-1042 2 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation

Ravasz, D., Kacso, G., Fodor, V., Horvath, K., Adam-Vizi, V. & Chinopoulos, C., Oct 2017, In : Neurochemistry international. 109, p. 41-53 13 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Divalent cation chelators citrate and EDTA unmask an intrinsic uncoupling pathway in isolated mitochondria

Starkov, A. A., Chinopoulos, C., Starkova, N. N., Konrad, C., Kiss, G., Stepanova, A. & Popov, V. N., Feb 1 2017, In : Journal of Bioenergetics and Biomembranes. 49, 1, p. 3-11 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2016

Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage

Németh, B., Doczi, J., Csete, D., Kacso, G., Ravasz, D., Adams, D., Kiss, G., Nagy, A. M., Horvath, G., Tretter, L., Mócsai, A., Csépányi-Kömi, R., Iordanov, I., Adam-Vizi, V. & Chinopoulos, C., Jan 1 2016, In : FASEB Journal. 30, 1, p. 286-300 15 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells

Doczi, J., Torocsik, B., Echaniz-Laguna, A., De Camaret, B. M., Starkov, A., Starkova, N., Gál, A., Molńr, M. J., Kawamata, H., Manfredi, G., Adam-Vizi, V. & Chinopoulos, C., May 25 2016, In : Scientific reports. 6, 26700.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Cyclophilin D regulates lifespan and protein expression of aging markers in the brain of mice

Vereczki, V., Mansour, J., Pour-Ghaz, I., Bodnár, I., Pinter, O., Zelena, D., Oszwald, E., Ádám-Vizi, V. & Chinopoulos, C., Jun 13 2016, (Accepted/In press) In : Mitochondrion.

Research output: Contribution to journalArticle

3 Citations (Scopus)
115 Citations (Scopus)

The total and mitochondrial lipidome of Artemia franciscana encysted embryos

Chen, E., Kiebish, M. A., McDaniel, J., Gao, F., Narain, N. R., Sarangarajan, R., Kacso, G., Ravasz, D., Seyfried, T. N., Adam-Vizi, V. & Chinopoulos, C., Nov 1 2016, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1861, 11, p. 1727-1735 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2015

Cyclophilin D disruption attenuates lipopolysaccharide-induced inflammatory response in primary mouse macrophages

Priber, J., Fonai, F., Jakus, P. B., Racz, B., Chinopoulos, C., Tretter, L., Gallyas, F., Sumegi, B. & Veres, B., Jan 23 2015, In : Biochemistry and Cell Biology. 93, 3, p. 241-250 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Erratum: Molecular mechanisms of cell death: Central implication of ATP synthase in mitochondrial permeability transition (Oncogene (2015) 34 (1475-1486 ) DOI: 10.1038/onc.2014.96)

Bonora, M., Wieckowsk, M. R., Chinopoulos, C., Kepp, O., Kroemer, G., Galluzzi, L. & Pinton, P., Mar 19 2015, In : Oncogene. 34, 12, 1 p.

Research output: Contribution to journalComment/debate

36 Citations (Scopus)

Exclusive neuronal expression of SUCLA2 in the human brain

Dobolyi, A., Ostergaard, E., Bagó, A. G., Dóczi, T., Palkovits, M., Gál, A., Molnár, M. J., Adam-Vizi, V. & Chinopoulos, C., Jan 1 2015, In : Brain Structure and Function. 220, 1, p. 135-151 17 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Molecular mechanisms of cell death: Central implication of ATP synthase in mitochondrial permeability transition

Bonora, M., Wieckowski, M. R., Chinopoulos, C., Kepp, O., Kroemer, G., Galluzzi, L. & Pinton, P., Mar 19 2015, In : Oncogene. 34, 12, p. 1475-1486 12 p.

Research output: Contribution to journalReview article

168 Citations (Scopus)
2014
5 Citations (Scopus)

Measurement of ADP-ATP exchange in relation to mitochondrial transmembrane potential and oxygen consumption

Chinopoulos, C., Kiss, G., Kawamata, H. & Starkov, A. A., 2014, Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism. Academic Press Inc., p. 333-348 16 p. (Methods in Enzymology; vol. 542).

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Citations (Scopus)

Mitochondrial diaphorases as NAD+ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition

Kiss, G., Konrad, C., Pour-Ghaz, I., Mansour, J. J., Németh, B., Starkov, A. A., Adam-Vizi, V. & Chinopoulos, C., Apr 2014, In : FASEB Journal. 28, 4, p. 1682-1697 16 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2013

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation

Kiss, G., Konrad, C., Doczi, J., Starkov, A. A., Kawamata, H., Manfredi, G., Zhang, S. F., Gibson, G. E., Beal, M. F., Adam-Vizi, V. & Chinopoulos, C., Jun 1 2013, In : FASEB Journal. 27, 6, p. 2393-2406 14 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

The Suppressor of AAC2 Lethality SAL1 Modulates Sensitivity of Heterologously Expressed Artemia ADP/ATP Carrier to Bongkrekate in Yeast

Wysocka-Kapcinska, M., Torocsik, B., Turiak, L., Tsaprailis, G., David, C. L., Hunt, A. M., Vekey, K., Adam-Vizi, V., Kucharczyk, R. & Chinopoulos, C., Sep 20 2013, In : PloS one. 8, 9, e74187.

Research output: Contribution to journalArticle

6 Citations (Scopus)

What makes you can also break you: Mitochondrial permeability transition pore formation by the c subunit of the F1F0 ATP-synthase?

Chinopoulos, C. & Szabadkai, G., Dec 24 2013, In : Frontiers in Oncology. 3 FEB, Article 00025.

Research output: Contribution to journalComment/debate

8 Citations (Scopus)

What makes you can also break you, part II: Mitochondrial permeability transition pore formation by dimers of the F1FO ATP-synthase?

Szabadkai, G. & Chinopoulos, C., Dec 31 2013, In : Frontiers in Oncology. 3 MAY, Article 140.

Research output: Contribution to journalComment/debate

5 Citations (Scopus)
56 Citations (Scopus)
2012
8 Citations (Scopus)
23 Citations (Scopus)

Quantitative measurement of mitochondrial membrane potential in cultured cells: Calcium-induced de- and hyperpolarization of neuronal mitochondria

Gerencser, A. A., Chinopoulos, C., Birket, M. J., Jastroch, M., Vitelli, C., Nicholls, D. G. & Brand, M. D., Jun 1 2012, In : Journal of Physiology. 590, 12, p. 2845-2871 27 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)
2011
9 Citations (Scopus)

adPEO mutations in ANT1 impair ADP-ATP translocation in muscle mitochondria

Kawamata, H., Tiranti, V., Magrané, J., Chinopoulos, C. & Manfredi, G., Aug 2011, In : Human molecular genetics. 20, 15, p. 2964-2974 11 p., ddr200.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Complex contribution of cyclophilin D to Ca2+-induced permeability transition in brain mitochondria, with relation to the bioenergetic state

Doczi, J., Turiák, L., Vajda, S., Mándi, M., Töröcsik, B., Gerencser, A. A., Kiss, G., Konràd, C., Adam-Vizi, V. & Chinopoulos, C., Feb 25 2011, In : Journal of Biological Chemistry. 286, 8, p. 6345-6353 9 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Isolation and functional assessment of mitochondria from small amounts of mouse brain tissue

Chinopoulos, C., Zhang, S. F., Thomas, B., Ten, V. & Starkov, A. A., Oct 24 2011, Neurodegeneration: Methods and Protocols. Manfredi, G. & Kawamata, H. (eds.). p. 311-324 14 p. (Methods in Molecular Biology; vol. 793).

Research output: Chapter in Book/Report/Conference proceedingChapter

27 Citations (Scopus)

Mitochondrial consumption of cytosolic ATP: Not so fast

Chinopoulos, C., May 6 2011, In : FEBS letters. 585, 9, p. 1255-1259 5 p.

Research output: Contribution to journalReview article

45 Citations (Scopus)

Modulation of F0F1-ATP synthase activity by cyclophilin D regulates matrix adenine nucleotide levels

Chinopoulos, C., Konràd, C., Kiss, G., Metelkin, E., Töröcsik, B., Zhang, S. F. & Starkov, A. A., Apr 1 2011, In : FEBS Journal. 278, 7, p. 1112-1125 14 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

The "B space" of mitochondrial phosphorylation

Chinopoulos, C., Dec 1 2011, In : Journal of Neuroscience Research. 89, 12, p. 1897-1904 8 p.

Research output: Contribution to journalShort survey

22 Citations (Scopus)
2010

A kinetic assay of mitochondrial ADP-ATP exchange rate in permeabilized cells

Kawamata, H., Starkov, A. A., Manfredi, G. & Chinopoulos, C., Dec 2010, In : Analytical Biochemistry. 407, 1, p. 52-57 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Forward operation of adenine nucleotide translocase during F 0F1-ATPase reversal: Critical role of matrix substrate-level phosphorylation

Chinopoulos, C., Gerencser, A. A., Mandi, M., Mathe, K., Töröcsik, B., Doczi, J., Turiak, L., Kiss, G., Konràd, C., Vajda, S., Vereczki, V., Oh, R. J. & Adam-Vizi, V., Jul 1 2010, In : FASEB Journal. 24, 7, p. 2405-2416 12 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Mitochondria as ATP consumers in cellular pathology

Chinopoulos, C. & Adam-Vizi, V., Jan 1 2010, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1802, 1, p. 221-227 7 p.

Research output: Contribution to journalReview article

56 Citations (Scopus)

Mitochondrial Ca2+ sequestration and precipitation revisited: Minireview

Chinopoulos, C. & Adam-Vizi, V., Sep 1 2010, In : FEBS Journal. 277, 18, p. 3637-3651 15 p.

Research output: Contribution to journalShort survey

43 Citations (Scopus)