• 4997 Citations
  • 38 h-Index
1978 …2019

Research output per year

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Research Output

  • 4997 Citations
  • 38 h-Index
  • 154 Article
  • 7 Chapter
  • 7 Review article
  • 1 Comment/debate
2019

Environmental history of the Csorna plain (Western Danube plain, NW Hungary) from the late glacial to the late Holocene as seen from data of multiproxy geoarchaeological investigations

Törőcsik, T., Gulyás, S., Sümegi, P., Sümegi, B., Molnár, D. & Benyó-Korcsmáros, R., Jan 1 2019, In : Studia Quaternaria. 36, 1, p. 19-43 25 p.

Research output: Contribution to journalArticle

PARP inhibitor PJ34 protects mitochondria and induces DNA-damage mediated apoptosis in combination with cisplatin or temozolomide in B16F10 melanoma cells

Cseh, A. M., Fabian, Z., Quintana-Cabrera, R., Szabo, A., Eros, K., Soriano, M. E., Gallyas, F., Scorrano, L. & Sumegi, B., Jan 1 2019, In : Frontiers in Physiology. 10, MAY, 538.

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

PARP inhibitor protects against chronic hypoxia/ reoxygenation-induced retinal injury by regulation of MAPKs, HIF1α, Nrf2, and NFjB

Kovacs, K., Vaczy, A., Fekete, K., Petra Kovari, K., Atlasz, T., Reglodi, D., Gabriel, R., Gallyas, F. & Sumegi, B., Apr 2019, In : Investigative Ophthalmology and Visual Science. 60, 5, p. 1478-1490 13 p.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Relict Anthropogenic Ecosystem from the Middle Ages: History of a Salt Marsh from Transylvania (Sic, N Romania)

Jakab, G., Silye, L., Sümegi, P., Tóth, A., Sümegi, B., Pál, I. & Benkő, E., Jan 1 2019, In : Environmental Archaeology.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2018

Activation of mitochondrial fusion provides a new treatment for mitochondria-related diseases

Szabó, A., Sumegi, K., Fekete, K., Hocsak, E., Debreceni, B., Setalo, G., Kovacs, K., Deres, L., Kengyel, A., Kovacs, D., Mandl, J., Nyitrai, M., Febbraio, M. A., Gallyas, F. & Sümegi, B., Apr 1 2018, In : Biochemical Pharmacology. 150, p. 86-96 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Amiodarone’s major metabolite, desethylamiodarone, induces apoptosis in human cervical cancer cells

Bognár, Z., Fekete, K., Bognar, R., Szabó, A., Vass, R. A. & Sümegi, B., Jan 1 2018, In : Canadian Journal of Physiology and Pharmacology. 96, 10, p. 1004-1011 8 p.

Research output: Contribution to journalArticle

Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases

Berger, N. A., Besson, V. C., Boulares, A. H., Bürkle, A., Chiarugi, A., Clark, R. S., Curtin, N. J., Cuzzocrea, S., Dawson, T. M., Dawson, V. L., Haskó, G., Liaudet, L., Moroni, F., Pacher, P., Radermacher, P., Salzman, A. L., Snyder, S. H., Soriano, F. G., Strosznajder, R. P., Sümegi, B. & 2 others, Swanson, R. A. & Szabo, C., Jan 1 2018, In : British journal of pharmacology. 175, 2, p. 192-222 31 p.

Research output: Contribution to journalReview article

47 Citations (Scopus)
4 Citations (Scopus)

The environmental history of a former salt town in Transylvania (Sic, Northern Romania)

Jakab, G., Silye, L., Sümegi, P., Törocsik, T., Tóth, A., Sümegi, B. & Benko, E., Jun 1 2018, In : Acta Archaeologica Academiae Scientiarum Hungaricae. 69, 1, p. 185-206 22 p.

Research output: Contribution to journalArticle

2017

Cardioprotective effect of resveratrol in a postinfarction heart failure model

Riba, A., Deres, L., Sümegi, B., Tóth, K., Szabados, E. & Halmosi, R., Jan 1 2017, In : Oxidative Medicine and Cellular Longevity. 2017, 6819281.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Chronic PARP-1 inhibition reduces carotid vessel remodeling and oxidative damage of the dorsal hippocampus in spontaneously hypertensive rats

Eros, K., Magyar, K., Deres, L., Skazel, A., Riba, A., Vamos, Z., Kalai, T., Gallyas, F., Sümegi, B., Tóth, K. & Halmosi, R., Mar 1 2017, In : PLoS One. 12, 3, e0174401.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Desethylamiodarone—A metabolite of amiodarone—Induces apoptosis on T24 human bladder cancer cells via multiple pathways

Bognár, Z., Fekete, K., Antus, C., Hocsak, E., Bognar, R., Tapodi, A., Boronkai, A., Farkas, N., Gallyas, F., Sümegi, B. & Szanto, A., Dec 1 2017, In : PLoS One. 12, 12, e0189470.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Doxycycline protects against ROS-induced mitochondrial fragmentation and ISOinduced heart failure

Riba, A., Deres, L., Eros, K., Szabó, A., Magyar, K., Sümegi, B., Tóth, K., Halmosi, R. & Szabados, E., Apr 1 2017, In : PLoS One. 12, 4, e0175195.

Research output: Contribution to journalArticle

18 Citations (Scopus)

PARP inhibition protects mitochondria and reduces ROS production via PARP-1-ATF4-MKP-1-MAPK retrograde pathway

Hocsak, E., Szabo, V., Kalman, N., Antus, C., Cseh, A., Sumegi, K., Eros, K., Hegedűs, Z., Gallyas, F., Sümegi, B. & Rácz, B., Jul 1 2017, In : Free Radical Biology and Medicine. 108, p. 770-784 15 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Poly(adenosine diphosphate-ribose) polymerase as therapeutic target: Lessons learned from its inhibitors

Cseh, A. M., Fábián, Z., Sümegi, B. & Scorrano, L., Jan 1 2017, In : Oncotarget. 8, 30, p. 50221-50239 19 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)
2016

PARP inhibition and postinfarction myocardial remodeling

Halmosi, R., Deres, L., Gal, R., Eros, K., Sümegi, B. & Tóth, K., Aug 1 2016, In : International Journal of Cardiology. 217, p. S52-S59

Research output: Contribution to journalArticle

6 Citations (Scopus)
2015

Anti-inflammatory effects of a triple-bond resveratrol analog: Structure and function relationship

Antus, C., Radnai, B., Dombovari, P., Fonai, F., Avar, P., Matyus, P., Racz, B., Sumegi, B. & Veres, B., Feb 5 2015, In : European Journal of Pharmacology. 748, p. 61-67 7 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Cyclophilin D disruption attenuates lipopolysaccharide-induced inflammatory response in primary mouse macrophages

Priber, J., Fonai, F., Jakus, P. B., Racz, B., Chinopoulos, C., Tretter, L., Gallyas, F., Sumegi, B. & Veres, B., Jan 23 2015, In : Biochemistry and Cell Biology. 93, 3, p. 241-250 10 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Lack of cyclophilin D protects against the development of acute lung injury in endotoxemia

Fonai, F., Priber, J. K., Jakus, P. B., Kalman, N., Antus, C., Pollak, E., Karsai, G., Tretter, L., Sumegi, B. & Veres, B., Dec 1 2015, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1852, 12, p. 2563-2573 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Role of mitochondrial network stabilisation by a human small heat shock protein in tumour malignancy

Turi, Z., Hocsak, E., Racz, B., Szabo, A., Balogh, A., Sumegi, B. & Gallyas, F., Jan 1 2015, In : Journal of Cancer. 6, 5, p. 470-476 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2014
14 Citations (Scopus)

Hemorheological parameters in coronary artery disease detected by multi-slice CT

Toth, A., Szukits, S., Varady, E., Sandor, B., Rabai, M., Papp, J., Juricskay, I., Kesmarky, G., Toth, K., Sumegi, B. & Battyani, I., 2014, In : Korea Australia Rheology Journal. 26, 2, p. 229-235 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Mitokondrium, oxidatív stressz és öregedés

Translated title of the contribution: Mitochondria, oxidative stress and agingSzarka, A., Bánhegyi, G. & Sümegi, B., Jan 1 2014, In : Orvosi hetilap. 155, 12, p. 447-452 6 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Novel mechanisms of sildenafil in pulmonary hypertension involving cytokines/chemokines, MAP kinases and Akt

Kiss, T., Kovacs, K., Komocsi, A., Tornyos, A., Zalan, P., Sumegi, B. & Gallyas, F., Aug 18 2014, In : PloS one. 9, 8, e104890.

Research output: Contribution to journalArticle

25 Citations (Scopus)
1 Citation (Scopus)
17 Citations (Scopus)

Quantification of conversion degree and monomer elution from dental composite using HPLC and micro-Raman spectroscopy

Lempel, E., Czibulya, Z., Kunsági-Máté, S., Szalma, J., Sümegi, B. & Böddi, K., Jan 1 2014, In : Chromatographia. 77, 17-18, p. 1137-1144 8 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2013

Antioxidant and Anti-Inflammatory Effects in RAW264.7 Macrophages of Malvidin, a Major Red Wine Polyphenol

Bognar, E., Sarszegi, Z., Szabo, A., Debreceni, B., Kalman, N., Tucsek, Z., Sumegi, B. & Gallyas, F., Jun 5 2013, In : PloS one. 8, 6, e65355.

Research output: Contribution to journalArticle

84 Citations (Scopus)

Hydroximic acid derivatives: Pleiotropic Hsp co-inducers restoring homeostasis and robustness

Crul, T., Toth, N., Piotto, S., Literati-Nagy, P., Tory, K., Haldimann, P., Kalmar, B., Greensmith, L., Torok, Z., Balogh, G., Gombos, I., Campana, F., Concilio, S., Gallyas, F., Nagy, G., Berente, Z., Gungor, B., Peter, M., Glatz, A., Hunya, A. & 20 others, Literati-Nagy, Z., Vigh, L., Hoogstra-Berends, F., Heeres, A., Kuipers, I., Loen, L., Seerden, J. P., Zhang, D., Meijering, R. A. M., Henning, R. H., Brundel, B. J. J. M., Kampinga, H. H., Koranyi, L., Szilvassy, Z., Mandl, J., Sumegi, B., Febbraio, M. A., Horvath, I., Hooper, P. L. & Vigh, L., Jan 1 2013, In : Current pharmaceutical design. 19, 3, p. 309-346 38 p.

Research output: Contribution to journalReview article

40 Citations (Scopus)

Mitigation of radiation injury by selective stimulation of the LPA 2 receptor

Kiss, G. N., Lee, S. C., Fells, J. I., Liu, J., Valentine, W. J., Fujiwara, Y., Thompson, K. E., Yates, C. R., Sümegi, B. & Tigyi, G., Jan 1 2013, In : Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1831, 1, p. 117-125 9 p.

Research output: Contribution to journalReview article

20 Citations (Scopus)

PARP inhibition attenuates acute kidney allograft rejection by suppressing cell death pathways and activating PI-3K-Akt cascade

Kalmar-Nagy, K., Degrell, P., Szabo, A., Sumegi, K., Wittmann, I., Gallyas, F. & Sumegi, B., Dec 3 2013, In : PloS one. 8, 12, e81928.

Research output: Contribution to journalArticle

9 Citations (Scopus)
19 Citations (Scopus)

Resveratrol and Oxidative Stress in Diabetes Mellitus

Brasnyó, P., Sümegi, B., Winkler, G. & Wittmann, I., Nov 1 2013, Diabetes: Oxidative Stress and Dietary Antioxidants. Elsevier Inc., p. 99-109 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

TRAF6 is functional in inhibition of TLR4-mediated NF-κB activation by resveratrol

Jakus, P. B., Kalman, N., Antus, C., Radnai, B., Tucsek, Z., Gallyas, F., Sumegi, B. & Veres, B., May 1 2013, In : Journal of Nutritional Biochemistry. 24, 5, p. 819-823 5 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2012

BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases

Sarszegi, Z., Bognar, E., Gaszner, B., Kónyi, A., Gallyas, F., Sumegi, B. & Berente, Z., Jun 1 2012, In : Molecular and Cellular Biochemistry. 365, 1-2, p. 129-137 9 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Cardioprotection by resveratrol: A human clinical trial in patients with stable coronary artery disease

Magyar, K., Halmosi, R., Palfi, A., Feher, G., Czopf, L., Fulop, A., Battyany, I., Sumegi, B., Toth, K. & Szabados, E., May 9 2012, In : Clinical hemorheology and microcirculation. 50, 3, p. 179-187 9 p.

Research output: Contribution to journalArticle

174 Citations (Scopus)
10 Citations (Scopus)

The HSP co-inducer BGP-15 can prevent the metabolic side effects of the atypical antipsychotics

Literáti-Nagy, Z., Tory, K., Literáti-Nagy, B., Kolonics, A., Török, Z., Gombos, I., Balogh, G., Vígh, L., Horváth, I., Mandl, J., Sümegi, B., Hooper, P. L. & Vígh, L., Jul 1 2012, In : Cell Stress and Chaperones. 17, 4, p. 517-521 5 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Virtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions

Kiss, G. N., Fells, J. I., Gupte, R., Lee, S. C., Liu, J., Nusser, N., Lim, K. G., Ray, R. M., Lin, F. T., Parrill, A. L., Sümegi, B., Miller, D. D. & Tigyi, G., Dec 1 2012, In : Molecular pharmacology. 82, 6, p. 1162-1173 12 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)
2011

HSP16.2 in cancers

Bellyei, S., Pozsgai, E. & Sumegi, B., Dec 1 2011, Small Stress Proteins and Human Diseases. Nova Science Publishers, Inc., p. 379-385 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Induction of mitochondrial destabilization and necrotic cell death by apolar mitochondria-directed SOD mimetics

Szabo, A., Balog, M., Mark, L., Montsko, G., Turi, Z., Gallyas, F., Sumegi, B., Kalai, T., Hideg, K. & Kovacs, K., May 1 2011, In : Mitochondrion. 11, 3, p. 476-487 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Regulation of kinase cascade activation and heat shock protein expression by poly(ADP-ribose) polymerase inhibition in doxorubicin-induced heart failure

Bartha, E., Solti, I., Szabo, A., Olah, G., Magyar, K., Szabados, E., Kalai, T., Hideg, K., Toth, K., Gero, D., Szabo, C., Sumegi, B. & Halmosi, R., Oct 1 2011, In : Journal of cardiovascular pharmacology. 58, 4, p. 380-391 12 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients

Brasnyó, P., Molnár, G. A., Mohás, M., Markó, L., Laczy, B., Cseh, J., Mikolás, E., Szijártó, I. A., Mérei, Á., Halmai, R., Mészáros, L. G., Sümegi, B. & Wittmann, I., Aug 14 2011, In : British Journal of Nutrition. 106, 3, p. 383-389 7 p.

Research output: Contribution to journalArticle

364 Citations (Scopus)

Suppressing LPS-induced early signal transduction in macrophages by a polyphenol degradation product: A critical role of MKP-1

Tucsek, Z., Radnai, B., Racz, B., Debreceni, B., Priber, J. K., Dolowschiak, T., Palkovics, T., Gallyas, F., Sumegi, B. & Veres, B., Jan 1 2011, In : Journal of Leukocyte Biology. 89, 1, p. 105-111 7 p.

Research output: Contribution to journalArticle

30 Citations (Scopus)

Synthesis and study of new paramagnetic resveratrol analogues

Kálai, T., Borza, E., Antus, C., Radnai, B., Gulyás-Fekete, G., Fehér, A., Sümegi, B. & Hideg, K., Dec 15 2011, In : Bioorganic and Medicinal Chemistry. 19, 24, p. 7311-7317 7 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2010

A novel PARP inhibitor L-2286 in a rat model of impact acceleration head injury: An immunohistochemical and behavioral study

Kövesdi, E., Bukovics, P., Besson, V., Nyirádi, J., Lückl, J., Pál, J., Sümegi, B., Dóczi, T., Hernádi, I. & Büki, A., Apr 1 2010, In : International journal of molecular sciences. 11, 4, p. 1253-1268 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Beneficial effect of the insulin sensitizer (HSP inducer) BGP-15 on olanzapine-induced metabolic disorders

Literáti-Nagy, B., Péterfai, É., Kulcsár, E., Literáti-Nagy, Z., Buday, B., Tory, K., Mandl, J., Sümegi, B., Fleming, A., Roth, J. & Korányi, L., Nov 20 2010, In : Brain Research Bulletin. 83, 6, p. 340-344 5 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)
43 Citations (Scopus)
23 Citations (Scopus)