• 485 Citations
  • 14 h-Index
19942018
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Research Output 1994 2018

  • 485 Citations
  • 14 h-Index
  • 44 Article
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Article
2018
1 Citation (Scopus)

Detection of stress and the effects of central nervous system depressants by gastrointestinal smooth muscle electromyography in wakeful rats

Szűcs, K. F., Grosz, G., Süle, M., Sztojkov-Ivanov, A., Ducza, E., Márki, A., Kothencz, A., Balogh, L. & Gáspár, R., Jul 15 2018, In : Life Sciences. 205, p. 1-8 8 p.

Research output: Contribution to journalArticle

Central Nervous System Depressants
Electromyography
Smooth Muscle
Muscle
Gastrointestinal Tract
1 Citation (Scopus)

Investigation of absorption routes of meloxicam and its salt form from intranasal delivery systems

Bartos, C., Ambrus, R., Kovács, A., Gáspár, R., Sztojkov-Ivanov, A., Márki, A., Janáky, T., T m si, F., Kecskeméti, G. & Szabó-Révész, P., Jan 1 2018, In : Molecules. 23, 4, 784.

Research output: Contribution to journalArticle

meloxicam
Nose
sprayers
Brain
delivery
2015
14 Citations (Scopus)

Study of sodium hyaluronate-based intranasal formulations containing micro- or nanosized meloxicam particles

Bartos, C., Ambrus, R., Sípos, P., Budai-Szucs, M., Csányi, E., Gáspár, R., Márki, A., Seres, A. B., Sztojkov-Ivanov, A., Horváth, T. & Szabó-Révész, P., Jul 6 2015, In : International Journal of Pharmaceutics. 491, 1-2, p. 198-207 10 p.

Research output: Contribution to journalArticle

meloxicam
Hyaluronic Acid
Particle Size
Area Under Curve
Electronic Nose
2014
1 Citation (Scopus)

Investigation of the pharmacokinetics of the ABCG2 transporter inhibitor Ko134 in mice by a newly developed and validated HPLC method

Sztojkov-Ivanov, A., Szolomajer-Csikós, O., Márki, A., Tóth, G. & Zupkó, I., 2014, In : Current Pharmaceutical Analysis. 10, 1, p. 30-37 8 p.

Research output: Contribution to journalArticle

Pharmacokinetics
High Pressure Liquid Chromatography
Drug Resistance
Adenosine Triphosphate
Pharmaceutical Preparations

Partial agonistic property of new isolated natural compounds

Ahmed, A. A. E., Gáspár, R., Márki, A., Mudawi, M. M. E. & Falkay, G., 2014, In : Journal of Chemical and Pharmaceutical Research. 6, 3, p. 1294-1298 5 p.

Research output: Contribution to journalArticle

Terbutaline
Adrenergic Receptors
Uterus
In Vitro Techniques
2013
25 Citations (Scopus)

In vitro and in vivo characterization of meloxicam nanoparticles designed for nasal administration

Kürti, L., Gáspár, R., Márki, A., Kápolna, E., Bocsik, A., Veszelka, S., Bartos, C., Ambrus, R., Vastag, M., Deli, M. & Szabó-Révész, P., 2013, In : European Journal of Pharmaceutical Sciences. 50, 1, p. 86-92 7 p.

Research output: Contribution to journalArticle

meloxicam
Intranasal Administration
Nanoparticles
Nose
Area Under Curve
16 Citations (Scopus)

Metabolic effects of mulberry leaves: Exploring potential benefits in type 2 diabetes and hyperuricemia

Hunyadi, A., Liktor-Busa, E., Márki, A., Martins, A., Jedlinszki, N., Hsieh, T. J., Báthori, M., Hohmann, J. & Zupkó, I., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 948627.

Research output: Contribution to journalArticle

Morus
Hyperuricemia
Gout Suppressants
Type 2 Diabetes Mellitus
Hypoglycemic Agents
2012
24 Citations (Scopus)
Methyl Ethers
HeLa Cells
Estrone
Cells
Cell Line
2011
1 Citation (Scopus)

In silico and in vitro pharmacological investigations of a natural alkaloid

Ahmed, A. A. E., Márki, A., Gáspár, R., Vasas, A., Mudawi, M. M. E., Jójárt, B., Minorics, R., Hohmann, J. & Falkay, G., 2011, (Accepted/In press) In : Medicinal Chemistry Research. p. 1-8 8 p.

Research output: Contribution to journalArticle

Terbutaline
Alkaloids
Computer Simulation
Adrenergic Receptors
Pharmacology
7 Citations (Scopus)

β 2-Adrenergic activity of 6-methoxykaempferol-3-O-glucoside on rat uterus: In vitro and in silico studies

Ahmed, A. A. E., Márki, A., Gáspár, R., Vasas, A., Mudawi, M. M. E., Verli, J., Jójárt, B., Hohmann, J. & Falkay, G., Sep 30 2011, In : European Journal of Pharmacology. 667, 1-3, p. 348-354 7 p.

Research output: Contribution to journalArticle

Computer Simulation
Adrenergic Agents
Uterus
Adrenergic Receptors
Terbutaline
2009
16 Citations (Scopus)
Alzheimer Disease
Hippocampal CA1 Region
Serum Amyloid A Protein
Iontophoresis
Tritium
4 Citations (Scopus)

Inflammatory processes enhance cAMP-mediated uterus relaxation in the pregnant rat: The role of TNF-α

Klukovits, A., Márki, A., Páldy, E., Benyhe, S., Gálik, M., Falkay, G. & Gáspár, R., May 2009, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 379, 5, p. 501-510 10 p.

Research output: Contribution to journalArticle

Terbutaline
Adrenergic Agonists
Uterus
Tumor Necrosis Factor-alpha
Thalidomide
2008
2 Citations (Scopus)

Humán interferon-α orális szilárd gyógyszerformába történo feldolgozása

Translated title of the contribution: Formulation of an oral solid dosage form containing human interferon-αKatalin, K., János, B., Márki, A., Erös, I., Falkay, G. & Pintye-Hódi, K., 2008, In : Acta Pharmaceutica Hungarica. 78, 1, p. 31-35 5 p.

Research output: Contribution to journalArticle

Dosage Forms
Interferons
Tablets
Gastric Juice
Ileum
86 Citations (Scopus)

Phytoecdysteroids and anabolic-androgenic steroids - Structure and effects on humans

Báthori, M., Tóth, N., Hunyadi, A., Márki, A. & Zádor, E., Jan 2008, In : Current Medicinal Chemistry. 15, 1, p. 75-91 17 p.

Research output: Contribution to journalArticle

Testosterone Congeners
Ecdysteroids
Steroids
Ecdysone
Vertebrates
2007
6 Citations (Scopus)

3D QSAR models for α2a-adrenoceptor agonists

Balogh, B., Jójárt, B., Wágner, Z., Kovács, P., Máté, G., Gyires, K., Zádori, Z., Falkay, G., Márki, A., Viskolcz, B. & Mátyus, P., Oct 2007, In : Neurochemistry International. 51, 5, p. 268-276 9 p.

Research output: Contribution to journalArticle

Quantitative Structure-Activity Relationship
Adrenergic Receptors
Structure-Activity Relationship
1 Citation (Scopus)

Modeling the human oxytocin receptor for drug discovery efforts

Jójárt, B., Balogh, B. & Márki, A., Dec 2007, In : Expert Opinion on Drug Discovery. 2, 12, p. 1579-1590 12 p.

Research output: Contribution to journalArticle

Oxytocin Receptors
Drug Discovery
Oxytocin
Ligands
Tocolysis
5 Citations (Scopus)
Benzoxazines
Molecular Dynamics Simulation
Anchors
Molecular Docking Simulation
Derivatives
9 Citations (Scopus)

Receptor-based QSAR studies of non-peptide human oxytocin receptor antagonists

Jójárt, B. & Márki, A., Jan 2007, In : Journal of Molecular Graphics and Modelling. 25, 5, p. 711-720 10 p.

Research output: Contribution to journalArticle

Bioactivity
activity (biology)
scoring
alignment
predictions
1 Citation (Scopus)

The effects of α-methyldopa on myometrial noradrenaline release and myometrial contractility in rat

Csonka, D., Zupkó, I., Minorics, R., Márki, A., Csík, G. & Falkay, G., 2007, In : Acta Obstetricia et Gynecologica Scandinavica. 86, 8, p. 986-994 9 p.

Research output: Contribution to journalArticle

Methyldopa
Norepinephrine
Adrenergic Agents
Terbutaline
Pregnancy
2006
4 Citations (Scopus)

Comparative study of eight oxytocin antagonists by simulated annealing

Jójárt, B. & Márki, A., Sep 2006, In : Journal of Molecular Modeling. 12, 6, p. 823-828 6 p.

Research output: Contribution to journalArticle

simulated annealing
Oxytocin
Dihedral angle
Simulated annealing
Amino acids
5 Citations (Scopus)
Trientine
Stereoisomerism
Estradiol
Isomers
Acetates
2005
25 Citations (Scopus)

Pregnancy-induced decrease in the relaxant effect of terbutaline in the late-pregnant rat myometrium: Role of G-protein activation and progesterone

Gáspár, R., Ducza, E., Mihályi, A., Márki, A., Kolarovszki-Sipiczki, Z., Páldy, E., Benyhe, S., Borsodi, A., Földesi, I. & Falkay, G., Jul 2005, In : Reproduction. 130, 1, p. 113-122 10 p.

Research output: Contribution to journalArticle

Terbutaline
Myometrium
GTP-Binding Proteins
Progesterone
Pregnancy
14 Citations (Scopus)
Benzoxazines
Quantitative Structure-Activity Relationship
scoring
Ligands
ligands
2004
13 Citations (Scopus)

Investigation of estrogen receptor α and β mRNA expression in the pregnant rat uterus

Minorics, R., Ducza, E., Márki, A., Páldy, E. & Falkay, G., Aug 2004, In : Molecular Reproduction and Development. 68, 4, p. 463-468 6 p.

Research output: Contribution to journalArticle

Estrogen Receptors
Uterus
Messenger RNA
Pregnancy
Progesterone Receptors
1 Citation (Scopus)

The role of androgen receptors in the dynamic process of prostate cancer: Their analytical determination in biopsy material

Pintér, O., Pajor, L., Molnár, J., Márki, A. & Falkay, G., Nov 2004, In : In Vivo. 18, 6, p. 809-812 4 p.

Research output: Contribution to journalArticle

Biopsy
Androgen Receptors
Prostatic Neoplasms
Cell growth
Prostate-Specific Antigen
2003
4 Citations (Scopus)

Kappa-receptor selective binding of opioid ligands with a heterocyclic bicyclo[3.3.1]nonan-9-one structure

Benyhe, S., Márki, A., Nachtsheim, C., Holzgrabe, U. & Borsodi, A., 2003, In : Acta Biologica Hungarica. 54, 2, p. 147-155 9 p.

Research output: Contribution to journalArticle

Benzomorphans
Ethylketocyclazocine
kappa Opioid Receptor
Molecular modeling
narcotics
33 Citations (Scopus)
Methyl Ethers
Estrone
Ethers
Derivatives
Estrogen Receptors
6 Citations (Scopus)

α-adrenergic blockade: A possible mechanism of tocolytic action of certain benzodiazepines in a postpartum rat model in vivo

Zupkó, I., Jánossy, K., Maul, K., Márki, A. & Falkay, G., Jan 24 2003, In : Life Sciences. 72, 10, p. 1093-1102 10 p.

Research output: Contribution to journalArticle

Tocolytic Agents
Benzodiazepines
Adrenergic Agents
Adrenergic Receptors
Postpartum Period
9 Citations (Scopus)

Noncompetitive nature of oxytocin antagonists with general structure Mpa1Xxx2Sar7Arg8

Havass, J., Bakos, K., Márki, A., Gáspár, R., Gera, L., Stewart, J. M., Fülöp, F., Tóth, G., Zupkó, I. & Falkay, G., Aug 2002, In : Peptides. 23, 8, p. 1419-1425 7 p.

Research output: Contribution to journalArticle

Oxytocin
Uterus
Pharmacology
Oxytocin Receptors
Vasopressin Receptors
15 Citations (Scopus)

Synthesis and receptor-binding examination of 16-hydroxymethyl-3,17-estradiol stereoisomers

Tapolcsányi, P., Wölfling, J., Falkay, G., Márki, A., Minorics, R. & Schneider, G., 2002, In : Steroids. 67, 7, p. 671-678 8 p.

Research output: Contribution to journalArticle

Stereoisomerism
Isomers
Estrogen Receptors
Estradiol
Radioligand Assay
10 Citations (Scopus)

Synthesis and receptor-binding examination of 16-hydroxymethyl-3,17-estradiol stereoisomers

Tapolcsányi, P., Wölfling, J., Falkay, G., Márki, A., Minorics, R. & Schneider, G., 2002, In : Steroids. 67, 5, p. 371-377 7 p.

Research output: Contribution to journalArticle

Stereoisomerism
Isomers
Estrogen Receptors
Estradiol
Radioligand Assay
2001
16 Citations (Scopus)
Uterine Contraction
Adrenergic Receptors
Progesterone
Rats
Estradiol

Farmakológiai modell az adrenerg rendszer szerepének vizsgálatára post partum patkány uteruson

Translated title of the contribution: Pharmacological model to investigate the role of the adrenergic system on post-partum rat uterusDucza, E., Gáspár, R., Márki, Á., Bottka, S. & Falkay, G., 2001, In : Acta Pharmaceutica Hungarica. 71, 3, p. 300-305 6 p.

Research output: Contribution to journalArticle

Antisense Oligonucleotides
Adrenergic Agents
Uterus
Pharmacology
Adrenergic Receptors
10 Citations (Scopus)
Antisense Oligonucleotides
Oligodeoxyribonucleotides
Adrenergic Receptors
Uterus
Tocolytic Agents
2000

A β-adrenerg receptorok spontan deszenzitizacoja terhes patkany uteruszon

Translated title of the contribution: Spontaneous desensitization of the β-adrenergic receptors in pregnant rat uterusGáspár, R., Márki, A., Mihalyi, A. & Falkay, G., 2000, In : Magyar Noorvosok Lapja. 63, 5, p. 377-380 4 p.

Research output: Contribution to journalArticle

Tocolysis
Adrenergic Receptors
Uterus
Terbutaline
Pregnancy
1999
10 Citations (Scopus)

Tritiated Kappa receptor antagonist norbinaltorphimine: Synthesis and in vitro binding in three different tissues

Márki, A., Ötvös, F., Tóth, G., Hosztafi, S. & Borsodi, A., Nov 26 1999, In : Life Sciences. 66, 1, p. 43-49 7 p.

Research output: Contribution to journalArticle

kappa Opioid Receptor
Tissue
Radioligand Assay
Tritium
Radioactivity
32 Citations (Scopus)

μ-Opioid receptor specific antagonist cyprodime: Characterization by in vitro radioligand and [35S]GTPγS binding assays

Márki, A., Monory, K., Ötvös, F., Tóth, G., Krassnig, R., Schmidhammer, H., Traynor, J. R., Roques, B. P., Maldonado, R. & Borsodi, A., Oct 27 1999, In : European Journal of Pharmacology. 383, 2, p. 209-214 6 p.

Research output: Contribution to journalArticle

Narcotic Antagonists
Opioid Receptors
Biological Assay
Morphine
Morphinans
1998
8 Citations (Scopus)
Adrenergic Receptors
Motor Activity
Uterus
Pharmacology
Tocolytic Agents
16 Citations (Scopus)

Evidence of non-synaptic regulation of postpartum uterine contractility in the rat

Gáspár, R., Márki, A., Zupkó, I. & Falkay, G., Feb 13 1998, In : Life Sciences. 62, 12, p. 1119-1124 6 p.

Research output: Contribution to journalArticle

Adrenergic Receptors
Postpartum Period
Rats
Phentolamine
Uterus
1997
15 Citations (Scopus)

New nepenthone and thevinone derivatives

Marton, J., Simon, C., Hosztafi, S., Szabó, Z., Márki, A., Borsodi, A. & Makleit, S., Feb 1997, In : Bioorganic and Medicinal Chemistry. 5, 2, p. 369-382 14 p.

Research output: Contribution to journalArticle

Opioid Receptors
Cyanamide
Derivatives
Cyanogen Bromide
Alkylation
1 Citation (Scopus)

Synthesis and opioid binding properties of new β-funaltrexamine (β-FNA) analogues

Simon, C., Hosztafi, S., Makleit, S., Márki, A., Benyhe, S. & Borsodi, A., 1997, In : Medicinal Chemistry Research. 7, 4, p. 251-258 8 p.

Research output: Contribution to journalArticle

Morphinans
Opioid Receptors
Opioid Analgesics
Ligands
1994
3 Citations (Scopus)

Mixed azines of naloxone with dihydromorphinone derivatives

Schmidhammer, H., Kaspar, F., Márki, A. & Borsodi, A., 1994, In : Helvetica Chimica Acta. 77, 4, p. 999-1002 4 p.

Research output: Contribution to journalArticle

morphine
Oxymorphone
Hydromorphone
azines
Opioid Receptors
15 Citations (Scopus)

Structurally novel group of ligands selective for kappa opioid receptors

Borsodi, A., Benyhe, S., Holzgrabe, U., Márki, A. & Nachtsheim, C., Nov 10 1994, In : Regulatory Peptides. 54, 1, p. 27-28 2 p.

Research output: Contribution to journalArticle

kappa Opioid Receptor
Ligands