• 6180 Citations
  • 33 h-Index
1985 …2020

Research output per year

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Research Output

  • 6180 Citations
  • 33 h-Index
  • 85 Article
  • 3 Review article
  • 1 Chapter
2020

Role of Mac-1 integrin in generation of extracellular vesicles with antibacterial capacity from neutrophilic granulocytes

Lőrincz, Á. M., Bartos, B., Szombath, D., Szeifert, V., Timár, C. I., Turiák, L., Drahos, L., Kittel, Á., Veres, D. S., Kolonics, F., Mócsai, A. & Ligeti, E., Jan 1 2020, In : Journal of Extracellular Vesicles. 9, 1, 1698889.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
2019
Open Access
9 Citations (Scopus)

En bloc release of MVB-like small extracellular vesicle clusters by colorectal carcinoma cells

Valcz, G., Buzás, E. I., Kittel, Á., Krenács, T., Visnovitz, T., Spisák, S., Török, G., Homolya, L., Zsigrai, S., Kiszler, G., Antalffy, G., Pálóczi, K., Szállási, Z., Szabó, V., Sebestyén, A., Solymosi, N., Kalmár, A., Dede, K., Lőrincz, P., Tulassay, Z. & 2 others, Igaz, P. & Molnár, B., Jan 1 2019, In : Journal of Extracellular Vesicles. 8, 1, 1596668.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

P2X7 receptors drive poly(I:C) induced autism-like behavior in mice

Horváth, G., Otrokocsi, L., Beko, K., Baranyi, M., Kittel, Á., Fritz-Ruenes, P. A. & Sperlágh, B., Mar 27 2019, In : Journal of Neuroscience. 39, 13, p. 2542-2561 20 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Radio-detoxified LPS alters bone marrow-derived extracellular vesicles and endothelial progenitor cells

Hegyesi, H., Sándor, N., Sáfrány, G., Lovas, V., Kovács, Á., Takács, A., Kohidai, L., Turiák, L., Kittel, Á., Pálóczi, K., Bertók, L. & Buzás, E. I., Oct 29 2019, In : Stem Cell Research and Therapy. 10, 1, 313.

Research output: Contribution to journalArticle

Open Access

Trafficking of immune cells across the bloodbrain barrier is modulated by neurofibrillary pathology in tauopathies

Majerova, P., Michalicova, A., Cente, M., Hanes, J., Vegh, J., Kittel, A., Kosikova, N., Cigankova, V., Mihaljevic, S., Jadhav, S. & Kovac, A., May 1 2019, In : PloS one. 14, 5, e0217216.

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
2018

Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype

Minakaki, G., Menges, S., Kittel, A., Emmanouilidou, E., Schaeffner, I., Barkovits, K., Bergmann, A., Rockenstein, E., Adame, A., Marxreiter, F., Mollenhauer, B., Galasko, D., Buzás, E. I., Schlötzer-Schrehardt, U., Marcus, K., Xiang, W., Lie, D. C., Vekrellis, K., Masliah, E., Winkler, J. & 1 others, Klucken, J., Jan 2 2018, In : Autophagy. 14, 1, p. 98-119 22 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

Cerebrovascular pathology in hypertriglyceridemic APOB-100 transgenic mice

Hoyk, Z., Tóth, M. E., Lénárt, N., Nagy, D., Dukay, B., Csefová, A., Zvara, Á., Seprényi, G., Kincses, A., Walter, F. R., Veszelka, S., Vígh, J., Barabási, B., Harazin, A., Kittel, Á., Puskás, L. G., Penke, B., Vígh, L., Deli, M. A. & Sántha, M., Oct 25 2018, In : Frontiers in Cellular Neuroscience. 12, 380.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Detection and proteomic characterization of extracellular vesicles in human pancreatic juice

Osteikoetxea, X., Benke, M., Rodriguez, M., Pálóczi, K., Sódar, B. W., Szvicsek, Z., Szabó-Taylor, K., Vukman, K. V., Kittel, Á., Wiener, Z., Vékey, K., Harsányi, L., Szűcs, Á., Turiák, L. & Buzás, E. I., Apr 30 2018, In : Biochemical and biophysical research communications. 499, 1, p. 37-43 7 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Isolation of high-purity extracellular vesicles by the combination of iodixanol density gradient ultracentrifugation and bind-elute chromatography from blood plasma

Onódi, Z., Pelyhe, C., Nagy, C. T., Brenner, G. B., Almási, L., Kittel, Á., Manček-Keber, M., Ferdinandy, P., Buzás, E. I. & Giricz, Z., Oct 23 2018, In : Frontiers in Physiology. 9, OCT, 1479.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Microglia control the spread of neurotropic virus infection via P2Y12 signalling and recruit monocytes through P2Y12-independent mechanisms

Fekete, R., Cserép, C., Lénárt, N., Tóth, K., Orsolits, B., Martinecz, B., Méhes, E., Szabó, B., Németh, V., Gönci, B., Sperlágh, B., Boldogkői, Z., Kittel, Á., Baranyi, M., Ferenczi, S., Kovács, K., Szalay, G., Rózsa, B., Webb, C., Kovacs, G. G. & 4 others, Hortobágyi, T., West, B. L., Környei, Z. & Dénes, Á., Sep 1 2018, In : Acta neuropathologica. 136, 3, p. 461-482 22 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2017

Antibiotic-induced release of small extracellular vesicles (exosomes) with surface-associated DNA

Németh, A., Orgovan, N., Sódar, B. W., Osteikoetxea, X., Pálóczi, K., Szabó-Taylor, K., Vukman, K. V., Kittel, Á., Turiák, L., Wiener, Z., Tóth, S., Drahos, L., Vékey, K., Horvath, R. & Buzás, E. I., Dec 1 2017, In : Scientific reports. 7, 1, 8202.

Research output: Contribution to journalArticle

35 Citations (Scopus)

Claudin peptidomimetics modulate tissue barriers for enhanced drug delivery

Dithmer, S., Staat, C., Müller, C., Ku, M. C., Pohlmann, A., Niendorf, T., Gehne, N., Fallier-Becker, P., Kittel, A., Walter, F. R., Veszelka, S., Deli, M. A., Blasig, R., Haseloff, R. F., Blasig, I. E. & Winkler, L., Jun 1 2017, In : Annals of the New York Academy of Sciences. 1397, 1, p. 169-184 16 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Effect of rat spinal cord injury (hemisection) on the ex vivo uptake and release of [3H]noradrenaline from a slice preparation

Borbély, Z., Csomó, B. K., Kittel, Á., Gerber, G., Varga, G. & Vizi, E. S., May 1 2017, In : Brain Research Bulletin. 131, p. 150-155 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Extracellular vesicles regulate the human osteoclastogenesis: divergent roles in discrete inflammatory arthropathies

Marton, N., Kovács, O. T., Baricza, E., Kittel, A., Győri, D., Mócsai, A., Meier, F. M. P., Goodyear, C. S., McInnes, I. B., Búzás, E. & Nagy, G., Oct 1 2017, In : Cellular and Molecular Life Sciences. 74, 19, p. 3599-3611 13 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

P2X7 receptors drive spine synapse plasticity in the learned helplessness model of depression

Otrokocsi, L., Kittel, Á. & Sperlágh, B., Oct 2017, In : International Journal of Neuropsychopharmacology. 20, 10, p. 813-822 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2016

Low-density lipoprotein mimics blood plasma-derived exosomes and microvesicles during isolation and detection

Sódar, B. W., Kittel, Á., Pálóczi, K., Vukman, K. V., Osteikoetxea, X., Szabó-Taylor, K., Németh, A., Sperlágh, B., Baranyai, T., Giricz, Z., Wiener, Z., Turiák, L., Drahos, L., Pállinger, É., Vékey, K., Ferdinandy, P., Falus, A. & Buzás, E. I., Apr 18 2016, In : Scientific reports. 6, 24316.

Research output: Contribution to journalArticle

158 Citations (Scopus)

Novel (Hetero)arylalkenyl propargylamine compounds are protective in toxin-induced models of Parkinson's disease

Baranyi, M., Porceddu, P. F., Gölöncsér, F., Kulcsár, S., Otrokocsi, L., Kittel, Á., Pinna, A., Frau, L., Huleatt, P. B., Khoo, M. L., Chai, C. L. L., Dunkel, P., Mátyus, P., Morelli, M. & Sperlágh, B., Jan 13 2016, In : Molecular Neurodegeneration. 11, 1, 6.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Restraint stress-induced morphological changes at the blood-brain barrier in adult rats

Sántha, P., Veszelka, S., Hoyk, Z., Mészáros, M., Walter, F. R., Tóth, A. E., Kiss, L., Kincses, A., Oláh, Z., Seprényi, G., Rákhely, G., Dér, A., Pákáski, M., Kálmán, J., Kittel, Á. & Deli, M. A., Jan 14 2016, In : Frontiers in Molecular Neuroscience. 8, JAN2016, 88.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2015

Differential detergent sensitivity of extracellular vesicle subpopulations

Osteikoetxea, X., Sódar, B., Németh, A., Szabó-Taylor, K., Pálóczi, K., Vukman, K. V., Tamási, V., Balogh, A., Kittel, Á., Pállinger, É. & Buzás, E. I., Aug 3 2015, In : Organic and Biomolecular Chemistry. 13, 38, p. 9775-9782 8 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Functionally and morphologically distinct populations of extracellular vesicles produced by human neutrophilic granulocytes

Lőrincz, Á. M., Schütte, M., Timár, C. I., Veres, D. S., Kittel, Á., McLeish, K. R., Merchant, M. L. & Ligeti, E., Oct 2015, In : Journal of Leukocyte Biology. 98, 4, p. 583-589 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Improved characterization of EV preparations based on protein to lipid ratio and lipid properties

Osteikoetxea, X., Balogh, A., Szabó-Taylor, K., Németh, A., Szabó, T. G., Pálóczi, K., Sódar, B., Kittel, Á., György, B., Pállinger, É., Matkó, J. & Buzás, E. I., Mar 23 2015, In : PloS one. 10, 3, e0121184.

Research output: Contribution to journalArticle

68 Citations (Scopus)

Isolation of exosomes from blood plasma: Qualitative and quantitative comparison of ultracentrifugation and size exclusion chromatography methods

Baranyai, T., Herczeg, K., Onódi, Z., Voszka, I., Módos, K., Marton, N., Nagy, G., Mäger, I., Wood, M. J., El Andaloussi, S., Pálinkás, Z., Kumar, V., Nagy, P., Kittel, Á., Buzás, E. I., Ferdinandy, P. & Giricz, Z., Dec 1 2015, In : PloS one. 10, 12, e0145686.

Research output: Contribution to journalArticle

196 Citations (Scopus)
2014

Critical role of extracellular vesicles in modulating the cellular effects of cytokines.

Szabó, G. T., Tarr, B., Pálóczi, K., Éder, K., Lajkó, E., Kittel, Á., Tóth, S., György, B., Pásztói, M., Németh, A., Osteikoetxea, X., Pállinger, É., Falus, A., Szabó-Taylor, K. & Buzás, E. I., Oct 2014, In : Cellular and molecular life sciences : CMLS. 71, 20, p. 4055-4067 13 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)

Effect of storage on physical and functional properties of extracellular vesicles derived from neutrophilic granulocytes

Lorincz, Á. M., Timár, C. I., Marosvári, K. A., Veres, D. S., Otrokocsi, L., Kittel, Á. & Ligeti, E., 2014, In : Journal of Extracellular Vesicles. 3, 1, 25465.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Sucrose esters increase drug penetration, but do not inhibit P-glycoprotein in Caco-2 intestinal epithelial cells

Kiss, L., Hellinger, É., Pilbat, A. M., Kittel, Á., Tö Rök, Z., Furedi, Szakács, G., Veszelka, S., Sipos, P., Ózsvári, B. É., Puskás, L. G., Vastag, M., Szabó -RÉVÉSZ, P. & Deli, M. A., Oct 12 2014, In : Journal of pharmaceutical sciences. 103, 10, p. 3107-3119 13 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)
2013

Antibacterial effect of microvesicles released from human neutrophilic granulocytes

Timár, C. I., Lorincz, Á. M., Csépányi-Kömi, R., Vályi-Nagy, A., Nagy, G., Buzás, E. I., Iványi, Z., Kittel, Á., Powell, D. W., McLeish, K. R. & Ligeti, E., Jan 17 2013, In : Blood. 121, 3, p. 510-518 9 p.

Research output: Contribution to journalArticle

96 Citations (Scopus)

Distinct RNA profiles in subpopulations of extracellular vesicles: Apoptotic bodies, microvesicles and exosomes

Crescitelli, R., Lässer, C., Szabó, T. G., Kittel, A., Eldh, M., Dianzani, I., Buzás, E. I. & Lötvall, J., 2013, In : Journal of Extracellular Vesicles. 2, 1, 20677.

Research output: Contribution to journalArticle

412 Citations (Scopus)

Label-free optical monitoring of surface adhesion of extracellular vesicles by grating coupled interferometry

Patko, D., Gyorgy, B., Nemeth, A., Szabó-Taylor, K. E., Kittel, A., Buzas, E. I. & Horvath, R., 2013, In : Sensors and Actuators, B: Chemical. 188, p. 697-701 5 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors

Csölle, C., Baranyi, M., Zsilla, G., Kittel, Á., Gölöncsér, F., Illes, P., Papp, E., Vizi, E. S. & Sperlágh, B., Jun 21 2013, In : PloS one. 8, 6, e66547.

Research output: Contribution to journalArticle

56 Citations (Scopus)
24 Citations (Scopus)
57 Citations (Scopus)

The recently identified hexosaminidase D enzyme substantially contributes to the elevated hexosaminidase activity in rheumatoid arthritis

Pásztói, M., Sódar, B., Misják, P., Pálóczi, K., Kittel, Á., Tóth, K., Wellinger, K., Géher, P., Nagy, G., Lakatos, T., Falus, A. & Buzás, E. I., Jan 1 2013, In : Immunology letters. 149, 1-2, p. 71-76 6 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2012

A purinerg jelátviteli rendszer szerepe depressziós kórképekben

Translated title of the contribution: The role of purinergic signaling in depressive disordersSperlagh, B., Csolle, C., Ando, R. D., Goloncser, F., Kittel, A. & Baranyi, M., Dec 1 2012, In : Neuropsychopharmacologia Hungarica. 14, 4, p. 231-238 8 p.

Research output: Contribution to journalReview article

42 Citations (Scopus)

Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood-brain barrier penetration models

Hellinger, É., Veszelka, S., Tóth, A. E., Walter, F., Kittel, Á., Bakk, M. L., Tihanyi, K., Háda, V., Nakagawa, S., Dinh Ha Duy, T., Niwa, M., Deli, M. A. & Vastag, M., Oct 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 82, 2, p. 340-351 12 p.

Research output: Contribution to journalArticle

113 Citations (Scopus)

Exposure to lipopolysaccharide and/or unconjugated bilirubin impair the integrity and function of brain microvascular endothelial cells

Cardoso, F. L., Kittel, Á., Veszelka, S., Palmela, I., Tóth, A., Brites, D., Deli, M. A. & Brito, M. A., May 7 2012, In : PloS one. 7, 5, e35919.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Improved Flow Cytometric Assessment Reveals Distinct Microvesicle (Cell-Derived Microparticle) Signatures in Joint Diseases

György, B., Szabó, T. G., Turiák, L., Wright, M., Herczeg, P., Lédeczi, Z., Kittel, Á., Polgár, A., Tóth, K., Dérfalvi, B., Zelenák, G., Böröcz, I., Carr, B., Nagy, G., Vékey, K., Gay, S., Falus, A. & Buzás, E. I., 2012, In : PloS one. 7, 11, e49726.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Presynaptic α2-adrenoceptors control the inhibitory action of presynaptic CB1 cannabinoid receptors on prefrontocortical norepinephrine release in the rat

Richter, H., Teixeira, F. M., Ferreira, S. G., Kittel, Á., Köfalvi, A. & Sperlágh, B., Oct 1 2012, In : Neuropharmacology. 63, 5, p. 784-797 14 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The effect of sucrose esters on a culture model of the nasal barrier

Kürti, L., Veszelka, S., Bocsik, A., Dung, N. T. K., Ózsvári, B., Puskás, L. G., Kittel, Á., Szabó-Révész, P. & Deli, M. A., Apr 1 2012, In : Toxicology in Vitro. 26, 3, p. 445-454 10 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

The medial habenula contains a specific nonstellate subtype of astrocyte expressing the ectonucleotidase NTPDase2

Gampe, K., Hammer, K., Kittel, Á. & Zimmermann, H., Dec 1 2012, In : Glia. 60, 12, p. 1860-1870 11 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2011

Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters

György, B., Módos, K., Pállinger, É., Pálóczi, K., Pásztói, M., Misják, P., Deli, M. A., Sipos, Á., Szalai, A., Voszka, I., Polgár, A., Tóth, K., Csete, M., Nagy, G., Gay, S., Falus, A., Kittel, Á. & Buzás, E. I., Jan 27 2011, In : Blood. 117, 4, p. e39-e48

Research output: Contribution to journalArticle

264 Citations (Scopus)

Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease

Hracská, Z., Baranyi, M., Csölle, C., Gölöncsér, F., Madarsz, E., Kittel, Á. & Sperlágh, B., 2011, In : Molecular Neurodegeneration. 6, 1, 28.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Membrane vesicles, current state-of-the-art: Emerging role of extracellular vesicles

György, B., Szabó, T. G., Pásztói, M., Pál, Z., Misják, P., Aradi, B., László, V., Pállinger, É., Pap, E., Kittel, Á., Nagy, G., Falus, A. & Buzás, E. I., Aug 2011, In : Cellular and Molecular Life Sciences. 68, 16, p. 2667-2688 22 p.

Research output: Contribution to journalReview article

1086 Citations (Scopus)

Oxygen-glucose deprivation increases the enzymatic activity and the microvesicle-mediated release of ectonucleotidases in the cells composing the blood-brain barrier

Ceruti, S., Colombo, L., Magni, G., Viganó, F., Boccazzi, M., Deli, M. A., Sperlágh, B., Abbracchio, M. P. & Kittel, Á., Aug 1 2011, In : Neurochemistry international. 59, 2, p. 259-271 13 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Proteomic characterization of thymocyte-derived microvesicles and apoptotic bodies in BALB/c mice

Turiák, L., Misják, P., Szabó, T. G., Aradi, B., Pálóczi, K., Ozohanics, O., Drahos, L., Kittel, Á., Falus, A., Buzás, E. I. & Vékey, K., Sep 6 2011, In : Journal of proteomics. 74, 10, p. 2025-2033 9 p.

Research output: Contribution to journalArticle

81 Citations (Scopus)

Tools for modelling blood-brain barrier penetrability

Veszelka, S., Kittel, Á. & Deli, M. A., Dec 1 2011, Solubility, Delivery and ADME Problems of Drugs and Drug-Candidates. Bentham Science Publishers Ltd., p. 166-188 23 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

14 Citations (Scopus)
2010

Protection of the blood-brain barrier by pentosan against amyloid-β-induced toxicity

Deli, M. A., Veszelka, S., Csiszár, B., Tóth, A., Kittel, Á., Csete, M., Sipos, Á., Szalai, A., Fülöp, L., Penke, B., Ábrahám, C. S. & Niwa, M., 2010, In : Journal of Alzheimer's Disease. 22, 3, p. 777-794 18 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
2009

A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

Nakagawa, S., Deli, M. A., Kawaguchi, H., Shimizudani, T., Shimono, T., Kittel, Á., Tanaka, K. & Niwa, M., Mar 2009, In : Neurochemistry international. 54, 3-4, p. 253-263 11 p.

Research output: Contribution to journalArticle

412 Citations (Scopus)

Gene expression and activity of cartilage degrading glycosidases in human rheumatoid arthritis and osteoarthritis synovial fibroblasts

Pásztói, M., Nagy, G., Géher, P., Lakatos, T., Tóth, K., Wellinger, K., Pócza, P., György, B., Holub, M. C., Kittel, Á., Pálóczy, K., Mazán, M., Nyirkos, P., Falus, A. & Buzas, E. I., May 14 2009, In : Arthritis Research and Therapy. 11, 3, R68.

Research output: Contribution to journalArticle

30 Citations (Scopus)
2008

Modulation of dopaminergic neurotransmission in rat striatum upon in vitro and in vivo diclofenac treatment

Milusheva, E., Baranyi, M., Kittel, A., Fekete, A., Zelles, T., Vizi, E. S. & Sperlágh, B., Apr 2008, In : Journal of neurochemistry. 105, 2, p. 360-368 9 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)