• 4420 Citations
  • 34 h-Index
19952019

Research output per year

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Research Output

  • 4420 Citations
  • 34 h-Index
  • 134 Article
  • 14 Review article
  • 5 Chapter
  • 1 Editorial
2019

Allele-specific RNA-seq expression profiling of imprinted genes in mouse isogenic pluripotent states

Dirks, R. A. M., Van Mierlo, G., Kerstens, H. H. D., Bernardo, A. S., Kobolák, J., Bock, I., Maruotti, J., Pedersen, R. A., Dinnyés, A., Huynen, M. A., Jouneau, A. & Marks, H., Feb 15 2019, In : Epigenetics and Chromatin. 12, 1, 14.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Generation of human induced pluripotent stem cell line UNIGEi001-A from a 2-years old patient with Mucopolysaccharidosis type IH disease

Lito, S., Burda, P., Baumgartner, M., Sloan-Béna, F., Táncos, Z., Kobolák, J., Dinnyés, A., Krause, K. H. & Marteyn, A., Dec 2019, In : Stem Cell Research. 41, 101604.

Research output: Contribution to journalArticle

Open Access

Light sheet fluorescence microscopy versus confocal microscopy: in quest of a suitable tool to assess drug and nanomedicine penetration into multicellular tumor spheroids

Lazzari, G., Vinciguerra, D., Balasso, A., Nicolas, V., Goudin, N., Garfa-Traore, M., Fehér, A., Dinnyés, A., Nicolas, J., Couvreur, P. & Mura, S., Sep 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 142, p. 195-203 9 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Modelling the neuropathology of lysosomal storage disorders through disease-specific human induced pluripotent stem cells

Kobolák, J., Molnár, K., Varga, E., Bock, I., Jezsó, B., Téglási, A., Zhou, S., Lo Giudice, M., Hoogeveen-Westerveld, M., Pijnappel, WWM. P., Phanthong, P., Varga, N., Kitiyanant, N., Freude, K., Nakanishi, H., László, L., Hyttel, P. & Dinnyés, A., Jul 15 2019, In : Experimental Cell Research. 380, 2, p. 216-233 18 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

SciChallenge: A Social Media Aware Platform for Contest-Based STEM Education and Motivation of Young Students

Achilleos, A. P., Mettouris, C., Yeratziotis, A., Papadopoulos, G. A., Pllana, S., Huber, F., Jäger, B., Leitner, P., Ocsovszky, Z. & Dinnyés, A., Jan 1 2019, In : IEEE Transactions on Learning Technologies. 12, 1, p. 98-111 14 p., 8305513.

Research output: Contribution to journalArticle

3 Citations (Scopus)

The nervous system relevance of the calcium sensing receptor in health and disease

Giudice, M. L., Mihalik, B., Dinnyés, A. & Kobolák, J., Jan 1 2019, In : Molecules. 24, 14, 2546.

Research output: Contribution to journalReview article

Open Access
3 Citations (Scopus)
2018

Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems

Pamies, D., Bal-Price, A., Chesné, C., Coecke, S., Dinnyés, A., Eskes, C., Grillari, R., Gstraunthaler, G., Hartung, T., Jennings, P., Leist, M., Martin, U., Passier, R., Schwamborn, J. C., Stacey, G. N., Ellinger-Ziegelbauer, H. & Daneshian, M., Jan 1 2018, In : Altex. 35, 3, p. 353-378 26 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state

Bernardo, A. S., Jouneau, A., Marks, H., Kensche, P., Kobolak, J., Freude, K., Hall, V., Feher, A., Polgar, Z., Sartori, C., Bock, I., Louet, C., Faial, T., Kerstens, H. H. D., Bouissou, C., Parsonage, G., Mashayekhi, K., Smith, J. C., Lazzari, G., Hyttel, P. & 4 others, Stunnenberg, H. G., Huynen, M., Pedersen, R. A. & Dinnyes, A., Jan 1 2018, In : Biology Open. 7, 8, bio033282.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The potency of induced pluripotent stem cells in cartilage regeneration and osteoarthritis treatment

Murphy, C., Mobasheri, A., Táncos, Z., Kobolák, J. & Dinnyés, A., Jan 1 2018, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 55-68 14 p. (Advances in Experimental Medicine and Biology; vol. 1079).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Three-dimensional analysis of nuclear heterochromatin distribution during early development in the rabbit

Bonnet-Garnier, A., Kiêu, K., Aguirre-Lavin, T., Tar, K., Flores, P., Liu, Z., Peynot, N., Chebrout, M., Dinnyés, A., Duranthon, V. & Beaujean, N., Sep 1 2018, In : Chromosoma. 127, 3, p. 387-403 17 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2017

Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism

Nagy, J., Kobolák, J., Berzsenyi, S., Ábrahám, Z., Avci, H. X., Bock, I., Bekes, Z., Hodoscsek, B., Chandrasekaran, A., Téglási, A., Dezső, P., Koványi, B., Vörös, E. T., Fodor, L., Szél, T., Németh, K., Balázs, A., Dinnyés, A., Lendvai, B., Lévay, G. & 1 others, Román, V., Jul 25 2017, In : Translational psychiatry. 7, 7, p. e1179

Research output: Contribution to journalArticle

10 Citations (Scopus)

Antimicrobial resistance of Lactobacillus spp. from fermented foods and human gut

Ma, Q., Fu, Y., Sun, H., Huang, Y., Li, L., Yu, Q., Dinnyés, A. & Sun, Q., Dec 1 2017, In : LWT - Food Science and Technology. 86, p. I

Research output: Contribution to journalArticle

4 Citations (Scopus)

Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells

Chandrasekaran, A., Avci, H. X., Ochalek, A., Rösingh, L. N., Molnár, K., László, L., Bellák, T., Téglási, A., Pesti, K., Mike, A., Phanthong, P., Bíró, O., Hall, V., Kitiyanant, N., Krause, K. H., Kobolák, J. & Dinnyés, A., Dec 1 2017, In : Stem Cell Research. 25, p. 139-151 13 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Enhancement of β-globin gene expression in thalassemic IVS2-654 induced pluripotent stem cell-derived erythroid cells by modified U7 snRNA

Phanthong, P., Borwornpinyo, S., Kitiyanant, N., Jearawiriyapaisarn, N., Nuntakarn, L., Saetan, J., Nualkaew, T., Sa-Ngiamsuntorn, K., Anurathapan, U., Dinnyes, A., Kitiyanant, Y. & Hongeng, S., Apr 2017, In : Stem Cells Translational Medicine. 6, 4, p. 1059-1069 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Establishment of an induced pluripotent stem cell (iPSC) line from a 9-year old male with autism spectrum disorder (ASD)

Varga, E., Nemes, C., Bock, I., Táncos, Z., Berzsenyi, S., Lévay, G., Román, V., Kobolák, J. & Dinnyés, A., May 1 2017, In : Stem Cell Research. 21, p. 19-22 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Establishment of a rabbit induced pluripotent stem cell (RbiPSC) line using lentiviral delivery of human pluripotency factors

Táncos, Z., Nemes, C., Varga, E., Bock, I., Rungarunlert, S., Tharasanit, T., Techakumphu, M., Kobolák, J. & Dinnyés, A., May 1 2017, In : Stem Cell Research. 21, p. 16-18 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Fragment-Based NMR Study of the Conformational Dynamics in the bHLH Transcription Factor Ascl1

Baronti, L., Hošek, T., Gil-Caballero, S., Raveh-Amit, H., Calçada, E. O., Ayala, I., Dinnyés, A., Felli, I. C., Pierattelli, R. & Brutscher, B., Apr 11 2017, In : Biophysical Journal. 112, 7, p. 1366-1373 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities

Schmidt, B. Z., Lehmann, M., Gutbier, S., Nembo, E., Noel, S., Smirnova, L., Forsby, A., Hescheler, J., Avci, H. X., Hartung, T., Leist, M., Kobolák, J. & Dinnyés, A., Jan 1 2017, In : Archives of Toxicology. 91, 1

Research output: Contribution to journalReview article

38 Citations (Scopus)

Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation

Ochalek, A., Mihalik, B., Avci, H. X., Chandrasekaran, A., Téglási, A., Bock, I., Giudice, M. L., Táncos, Z., Molnár, K., László, L., Nielsen, J. E., Holst, B., Freude, K., Hyttel, P., Kobolák, J. & Dinnyés, A., Dec 1 2017, In : Alzheimer's Research and Therapy. 9, 1, 90.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Systematic in vitro and in vivo characterization of Leukemia-inhibiting factor- and Fibroblast growth factor-derived porcine induced pluripotent stem cells

Secher, J. O., Ceylan, A., Mazzoni, G., Mashayekhi, K., Li, T., Muenthaisong, S., Nielsen, T. T., Li, D., Li, S., Petkov, S., Cirera, S., Luo, Y., Thombs, L., Kadarmideen, H. N., Dinnyes, A., Bolund, L., Roelen, B. A. J., Schmidt, M., Callesen, H., Hyttel, P. & 1 others, Freude, K. K., Mar 1 2017, In : Molecular Reproduction and Development. 84, 3, p. 229-245 17 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2016

Astrocyte differentiation of human pluripotent stem cells: New tools for neurological disorder research

Chandrasekaran, A., Avci, H. X., Leist, M., Kobolák, J. & Dinnyés, A., Sep 26 2016, In : Frontiers in Cellular Neuroscience. 10, SEP2016, 215.

Research output: Contribution to journalReview article

52 Citations (Scopus)

Controlled hydrostatic pressure stress downregulates the expression of ribosomal genes in preimplantation embryos: A possible protection mechanism?

Bock, I., Raveh-Amit, H., Losonczi, E., Carstea, A. C., Feher, A., Mashayekhi, K., Matyas, S., Dinnyés, A. & Pribenszky, C., 2016, In : Reproduction, Fertility and Development. 28, 6, p. 776-784 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Derivation of induced pluripotent stem cells from a familial Alzheimer's disease patient carrying the L282F mutation in presenilin 1

Poon, A., Li, T., Pires, C., Nielsen, T. T., Nielsen, J. E., Holst, B., Dinnyés, A., Hyttel, P. & Freude, K. K., Nov 1 2016, In : Stem Cell Research. 17, 3, p. 470-473 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Establishment of EHMT1 mutant induced pluripotent stem cell (iPSC) line from a 11-year-old Kleefstra syndrome (KS) patient with autism and normal intellectual performance

Varga, E., Nemes, C., Táncos, Z., Bock, I., Berzsenyi, S., Lévay, G., Román, V., Kobolák, J. & Dinnyés, A., Nov 1 2016, In : Stem Cell Research. 17, 3, p. 531-533 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Establishment of induced pluripotent stem cell (iPSC) line from a 57-year old patient with late onset Alzheimer's disease (LOAD)

Ochalek, A., Nemes, C., Varga, E., Táncos, Z., Kobolák, J. & Dinnyés, A., Jul 1 2016, In : Stem Cell Research. 17, 1, p. 72-74 3 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Establishment of induced pluripotent stem cell (iPSC) line from a 63-year old patient with late onset Alzheimer's disease (LOAD)

Chandrasekaran, A., Varga, E., Nemes, C., Táncos, Z., Kobolák, J. & Dinnyés, A., Jul 1 2016, In : Stem Cell Research. 17, 1, p. 78-80 3 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Establishment of induced pluripotent stem cell (iPSC) line from a 75-year old patient with late onset Alzheimer's disease (LOAD)

Táncos, Z., Varga, E., Kovács, E., Dinnyés, A. & Kobolák, J., Jul 1 2016, In : Stem Cell Research. 17, 1, p. 81-83 3 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Establishment of induced pluripotent stem cell (iPSC) line from an 84-year old patient with late onset Alzheimer's disease (LOAD)

Táncos, Z., Varga, E., Kovács, E., Dinnyés, A. & Kobolák, J., Jul 1 2016, In : Stem Cell Research. 17, 1, p. 75-77 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Establishment of PSEN1 mutant induced pluripotent stem cell (iPSC) line from an Alzheimer's disease (AD) female patient

Nemes, C., Varga, E., Táncos, Z., Bock, I., Francz, B., Kobolák, J. & Dinnyés, A., Jul 1 2016, In : Stem Cell Research. 17, 1, p. 69-71 3 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Generation of Cholinergic and Dopaminergic Interneurons from Human Pluripotent Stem Cells as a Relevant Tool for in Vitro Modeling of Neurological Disorders Pathology and Therapy

Ochalek, A., Szczesna, K., Petazzi, P., Kobolak, J. & Dinnyes, A., Jan 1 2016, In : Stem Cells International. 2016, 5838934.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Generation of human induced pluripotent stem cell (iPSC) line from an unaffected female carrier of Mucopolysaccharidosis type II (MPS II) disorder

Varga, E., Nemes, C., Kovács, E., Bock, I., Varga, N., Fehér, A., Dinnyés, A. & Kobolák, J., Nov 1 2016, In : Stem Cell Research. 17, 3, p. 514-516 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying a M146I mutation in PSEN1

Li, T., Pires, C., Nielsen, T. T., Waldemar, G., Hjermind, L. E., Nielsen, J. E., Dinnyés, A., Holst, B., Hyttel, P. & Freude, K. K., Mar 1 2016, In : Stem Cell Research. 16, 2, p. 334-337 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Generation of induced pluripotent stem cells (iPSCs) from an Alzheimer's disease patient carrying an A79V mutation in PSEN1

Li, T., Pires, C., Nielsen, T. T., Waldemar, G., Hjermind, L. E., Nielsen, J. E., Dinnyés, A., Hyttel, P. & Freude, K. K., Mar 1 2016, In : Stem Cell Research. 16, 2, p. 229-232 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Generation of Mucopolysaccharidosis type II (MPS II) human induced pluripotent stem cell (iPSC) line from a 1-year-old male with pathogenic IDS mutation

Varga, E., Nemes, C., Bock, I., Varga, N., Fehér, A., Dinnyés, A. & Kobolák, J., Nov 1 2016, In : Stem Cell Research. 17, 3, p. 482-484 3 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Generation of Mucopolysaccharidosis type II (MPS II) human induced pluripotent stem cell (iPSC) line from a 3-year-old male with pathogenic IDS mutation

Varga, E., Nemes, C., Bock, I., Varga, N., Fehér, A., Kobolák, J. & Dinnyés, A., Nov 1 2016, In : Stem Cell Research. 17, 3, p. 479-481 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Generation of Mucopolysaccharidosis type II (MPS II) human induced pluripotent stem cell (iPSC) line from a 7-year-old male with pathogenic IDS mutation

Varga, E., Nemes, C., Bock, I., Varga, N., Fehér, A., Kobolák, J. & Dinnyés, A., Nov 1 2016, In : Stem Cell Research. 17, 3, p. 463-465 3 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

In vitro models of cancer stem cells and clinical applications

Franco, S. S., Szczesna, K., Iliou, M. S., Al-Qahtani, M., Mobasheri, A., Kobolák, J. & Dinnyés, A., Jan 1 2016, In : BMC cancer. 16, 738.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Neurosphere based differentiation of human IPSC improves astrocyte differentiation

Zhou, S., Szczesna, K., Ochalek, A., Kobolák, J., Varga, E., Nemes, C., Chandrasekaran, A., Rasmussen, M., Cirera, S., Hyttel, P., Dinnyés, A., Freude, K. K. & Avci, H. X., 2016, In : Stem Cells International. 2016, 4937689.

Research output: Contribution to journalArticle

23 Citations (Scopus)

Novel bioreactor platform for scalable cardiomyogenic differentiation from pluripotent stem cell-derived embryoid bodies

Rungarunlert, S., Ferreira, J. N. & Dinnyes, A., 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1502. p. 169-179 11 p. (Methods in Molecular Biology; vol. 1502).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Targeted next generation sequencing of a panel of autism-related genes identifies an EHMT1 mutation in a Kleefstra syndrome patient with autism and normal intellectual performance

Bock, I., Németh, K., Pentelényi, K., Balicza, P., Balázs, A., Molnár, M. J., Román, V., Nagy, J., Lévay, G., Kobolák, J. & Dinnyés, A., Dec 31 2016, In : Gene. 595, 2, p. 131-141 11 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

The positional identity of iPSC-derived neural progenitor cells along the anterior-posterior axis is controlled in a dosage-dependent manner by bFGF and EGF

Zhou, S., Ochalek, A., Szczesna, K., Avci, H. X., Kobolák, J., Varga, E., Rasmussen, M., Holst, B., Cirera, S., Hyttel, P., Freude, K. K. & Dinnyés, A., Oct 1 2016, In : Differentiation. 92, 4, p. 183-194 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
2015

Cloning and characterization of rabbit POU5F1, SOX2, KLF4, C-MYC and NANOG pluripotency-associated genes

Táncos, Z., Bock, I., Nemes, C., Kobolák, J. & Dinnyés, A., Jul 25 2015, In : Gene. 566, 2, p. 148-157 10 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Grafted murine induced pluripotent stem cells prevent death of injured rat motoneurons otherwise destined to die

Pajer, K., Nemes, C., Berzsenyi, S., Kovács, K. A., Pirity, M. K., Pajenda, G., Nógrádi, A. & Dinnyés, A., Jul 1 2015, In : Experimental Neurology. 269, p. 188-201 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Human three-dimensional engineered neural tissue reveals cellular and molecular events following cytomegalovirus infection

Cosset, É., Martinez, Y., Preynat-Seauve, O., Lobrinus, J. A., Tapparel, C., Cordey, S., Peterson, H., Petty, T. J., Colaianna, M., Tieng, V., Tirefort, D., Dinnyes, A., Dubois-Dauphin, M., Kaiser, L. & Krause, K. H., Jun 1 2015, In : Biomaterials. 53, p. 296-308 13 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Lack of Rybp in Mouse Embryonic Stem Cells Impairs Cardiac Differentiation

Ujhelly, O., Szabo, V., Kovacs, G., Vajda, F., Mallok, S., Prorok, J., Acsai, K., Hegedus, Z., Krebs, S., Dinnyes, A. & Pirity, M. K., Sep 15 2015, In : Stem Cells and Development. 24, 18, p. 2193-2205 13 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Mesenchymal stem cells: Identification, phenotypic characterization, biological properties and potential for regenerative medicine through biomaterial micro-engineering of their niche

Kobolak, J., Dinnyés, A., Memic, A., Khademhosseini, A. & Mobasheri, A., May 2 2015, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

84 Citations (Scopus)

The crossroads between cancer stem cells and aging

Franco, S. S., Raveh-Amit, H., Kobolák, J., Alqahtani, M. H., Mobasheri, A. & Dinnyes, A., Jan 15 2015, In : BMC cancer. 15, 1, S1.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Towards understanding protein disorder in-cell

Cedeño, C., Raveh-Amit, H., Dinnyés, A. & Tompa, P., Sep 22 2015, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 319-334 16 p. (Advances in Experimental Medicine and Biology; vol. 870).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Vitrified sheep isolated secondary follicles are able to grow and form antrum after a short period of in vitro culture

Lunardi, F. O., Chaves, R. N., de Lima, L. F., Araújo, V. R., Brito, I. R., Souza, C. E. A., Donato, M. A. M., Peixoto, C. A., Dinnyes, A., Campello, C. C., de Figueiredo, J. R. & Rodrigues, A. P. R., Oct 22 2015, In : Cell And Tissue Research. 362, 1, p. 241-251 11 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2014

Autophagy is required for zebrafish caudal fin regeneration

Varga, M., Sass, M., Papp, D., Takács-Vellai, K., Kobolak, J., Dinnyés, A., Klionsky, D. J. & Vellai, T., Apr 1 2014, In : Cell Death and Differentiation. 21, 4, p. 547-556 10 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)