• 7922 Citations
  • 34 h-Index
1993 …2019

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2019

Assessment of temporal functional changes and miRNA profiling of human iPSC-derived cardiomyocytes

Kumar, N., Dougherty, J. A., Manring, H. R., Elmadbouh, I., Mergaye, M., Czirok, A., Greta Isai, D., Belevych, A. E., Yu, L., Janssen, P. M. L., Fadda, P., Gyorke, S., Ackermann, M. A., Angelos, M. G. & Khan, M., Dec 1 2019, In : Scientific reports. 9, 1, 13188.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Enhanced endothelial motility and multicellular sprouting is mediated by the scaffold protein TKS4

Mehes, E., Barath, M., Gulyas, M., Bugyik, E., Geiszt, M., Szoor, A., Lanyi, A. & Czirok, A., Dec 1 2019, In : Scientific reports. 9, 1, 14363.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Epigenetic Priming of Human Pluripotent Stem Cell-Derived Cardiac Progenitor Cells Accelerates Cardiomyocyte Maturation

Biermann, M., Cai, W., Lang, D., Hermsen, J., Profio, L., Zhou, Y., Czirok, A., Isai, D. G., Napiwocki, B. N., Rodriguez, A. M., Brown, M. E., Woon, M. T., Shao, A., Han, T., Park, D., Hacker, T. A., Crone, W. C., Burlingham, W. J., Glukhov, A. V., Ge, Y. & 1 others, Kamp, T. J., Jul 2019, In : Stem Cells. 37, 7, p. 910-923 14 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Matrigel patterning reflects multicellular contractility

Méhes, E., Biri-Kovács, B., Isai, D. G., Gulyás, M., Nyitray, L. & Czirók, A., 2019, In : PLoS computational biology. 15, 10, e1007431.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Polarization wave at the onset of collective cell migration

Oelz, D., Khataee, H., Czirok, A. & Neufeld, Z., Sep 5 2019, In : Physical Review E. 100, 3, 032403.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2018

Manipulation-free cultures of human iPSC-derived cardiomyocytes offer a novel screening method for cardiotoxicity

Rajasingh, S., Isai, D. G., Samanta, S., Zhou, Z. G., Dawn, B., Kinsey, W. H., Czirok, A. & Rajasingh, J., Oct 1 2018, In : Acta Pharmacologica Sinica. 39, 10, p. 1590-1603 14 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Nintedanib is active in malignant pleural mesothelioma cell models and inhibits angiogenesis and tumor growth in vivo

Laszlo, V., Valko, Z., Kovacs, I., Ozsvar, J., Hoda, M. A., Klikovits, T., Lakatos, D., Czirók, A., Garay, T., Stiglbauer, A., Helbich, T. H., Groger, M., Tóvári, J., Klepetko, W., Pirker, C., Grusch, M., Berger, W., Hilberg, F., Hegedus, B. & Döme, B., Aug 1 2018, In : Clinical Cancer Research. 24, 15, p. 3729-3740 12 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Pre-Conditioning Stem Cells in a Biomimetic Environment for Enhanced Cardiac Tissue Repair: In Vitro and In Vivo Analysis

Chakravarti, A. R., Pacelli, S., Alam, P., Bagchi, S., Modaresi, S., Czirok, A., Ahmed, R. P. H. & Paul, A., Oct 1 2018, In : Cellular and Molecular Bioengineering. 11, 5, p. 321-336 16 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Software tools for cell culture-related 3D printed structures

Gulyas, M., Csiszer, M., Mehes, E. & Czirok, A., Sep 2018, In : PloS one. 13, 9, e0203203.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Soluble VEGFR1 signaling guides vascular patterns into dense branching morphologies

Lakatos, D., Somfai, E., Méhes, E. & Czirók, A., Nov 7 2018, In : Journal of Theoretical Biology. 456, p. 261-278 18 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
2017

Bistable front dynamics in a contractile medium: Travelling wave fronts and cortical advection define stable zones of RhoA signaling at epithelial adherens junctions

Priya, R., Gomez, G. A., Budnar, S., Acharya, B. R., Czirok, A., Yap, A. S. & Neufeld, Z., Mar 2017, In : PLoS computational biology. 13, 3, e1005411.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Cell Dispersal Influences Tumor Heterogeneity and Introduces a Bias in NGS Data Interpretation

Pongor, L., Harami-Papp, H., Méhes, E., Czirók, A. & Gyorffy, B., Dec 1 2017, In : Scientific reports. 7, 1, 7358.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Optical-flow based non-invasive analysis of cardiomyocyte contractility

Czirok, A., Isai, D. G., Kosa, E., Rajasingh, S., Kinsey, W., Neufeld, Z. & Rajasingh, J., Dec 1 2017, In : Scientific reports. 7, 1, 10404.

Research output: Contribution to journalArticle

11 Citations (Scopus)

The role of Allee effect in modelling post resection recurrence of glioblastoma

Neufeld, Z., von Witt, W., Lakatos, D., Wang, J., Hegedus, B. & Czirok, A., Nov 2017, In : PLoS computational biology. 13, 11, e1005818.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2016

SPECC1L deficiency results in increased adherens junction stability and reduced cranial neural crest cell delamination

Wilson, N. R., Olm-Shipman, A. J., Acevedo, D. S., Palaniyandi, K., Hall, E. G., Kosa, E., Stumpff, K. M., Smith, G. J., Pitstick, L., Liao, E. C., Bjork, B. C., Czirok, A. & Saadi, I., Jan 20 2016, In : Scientific reports. 6, 17735.

Research output: Contribution to journalArticle

12 Citations (Scopus)
2015

Active cell and ECM movements during development

Aleksandrova, A., Rongish, B. J., Little, C. D. & Czirók, A., 2015, In : Methods in Molecular Biology. 1189, p. 123-132 10 p.

Research output: Contribution to journalArticle

Anomalous segregation dynamics of self-propelled particles

Mones, E., Czirók, A. & Vicsek, T., Jun 10 2015, In : New Journal of Physics. 17, 6, 063013.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Cell resolved, multiparticle model of plastic tissue deformations and morphogenesis

Czirok, A. & Isai, D. G., Feb 1 2015, In : Physical Biology. 12, 1, 016005.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Generation of functional cardiomyocytes from efficiently generated human iPSCs and a novel method of measuring contractility

Rajasingh, S., Thangavel, J., Czirok, A., Samanta, S., Roby, K. F., Dawn, B. & Rajasingh, J., Aug 3 2015, In : PloS one. 10, 8, e0134093.

Research output: Contribution to journalArticle

12 Citations (Scopus)

The endoderm and myocardium join forces to drive early heart tube assembly

Aleksandrova, A., Czirok, A., Kosa, E., Galkin, O., Cheuvront, T. J. & Rongish, B. J., Aug 1 2015, In : Developmental Biology. 404, 1, p. 40-54 15 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2014

Autocrine FGF feedback can establish distinct states of Nanog expression in pluripotent stem cells: A computational analysis

Lakatos, D., Travis, E. D., Pierson, K. E., Vivian, J. L. & Czirok, A., Sep 27 2014, In : BMC Systems Biology. 8, 1, 112.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2013

Cell migration or cytokinesis and proliferation? - Revisiting the "go or grow" hypothesis in cancer cells in vitro

Garay, T., Juhász, É., Molnár, E., Eisenbauer, M., Czirók, A., Dekan, B., László, V., Hoda, M. A., Döme, B., Tímár, J., Klepetko, W., Berger, W. & Hegedus, B., Dec 10 2013, In : Experimental Cell Research. 319, 20, p. 3094-3103 10 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)

Collective cell streams in epithelial monolayers depend on cell adhesion

Czirók, A., Varga, K., Méhes, E. & Szabó, A., Jul 2013, In : New Journal of Physics. 15, 075006.

Research output: Contribution to journalArticle

24 Citations (Scopus)
15 Citations (Scopus)
2012

Convective tissue movements play a major role in avian endocardial morphogenesis

Aleksandrova, A., Czirók, A., Szabó, A., Filla, M. B., Hossain, M. J., Whelan, P. F., Lansford, R. & Rongish, B. J., Mar 15 2012, In : Developmental Biology. 363, 2, p. 348-361 14 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Invasion from a cell aggregate - The roles of active cell motion and mechanical equilibrium

Czirók, A., Szabó, A., Varga, K., Garay, T., Hegeds, B., Szabó, A., Varga, K., Garay, T. & Hegeds, B., Feb 2012, In : Physical Biology. 9, 1, 016010.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2011

Extracellular matrix fluctuations during early embryogenesis

Szabó, A., Rupp, P. A., Rongish, B. J., Little, C. D. & Czirók, A., Aug 2011, In : Physical Biology. 8, 4, 045006.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Inhibition of myosin II triggers morphological transition and increased nuclear motility

Szabó, B., Ünnep, R., Markó, K., Környei, Z., Méhes, E. A. & Czirók, A., Jun 1 2011, In : Cytoskeleton. 68, 6, p. 325-339 15 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

The cytoplasmic domain of TGFβR3 through its interaction with the scaffolding protein, GIPC, directs epicardial cell behavior

Sánchez, N. S., Hill, C. R., Love, J. D., Soslow, J. H., Craig, E., Austin, A. F., Brown, C. B., Czirok, A., Camenisch, T. D. & Barnett, J. V., Oct 15 2011, In : Developmental Biology. 358, 2, p. 331-343 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2010

Collective cell motion in endothelial monolayers

Szabó, A., Ünnep, R., Méhes, E., Twal, W. O., Argraves, W. S., Cao, Y. & Czirók, A., Dec 2010, In : Physical Biology. 7, 4, 046007.

Research output: Contribution to journalArticle

110 Citations (Scopus)

Dynamic analysis of vascular morphogenesis using transgenic quail embryos

Sato, Y., Poynter, G., Huss, D., Filla, M. B., Czirok, A., Rongish, B. J., Little, C. D., Fraser, S. E. & Lansford, R., 2010, In : PloS one. 5, 9, p. 1-12 12 p., e12674.

Research output: Contribution to journalArticle

93 Citations (Scopus)
2008

Matrix metalloproteinase 2-integrin αvβ3 binding is required for mesenchymal cell invasive activity but not epithelial locomotion: A computational time-lapse study

Rupp, P. A., Visconti, R. P., Czirók, A., Cheresh, D. A. & Little, C. D., Dec 2008, In : Molecular Biology of the Cell. 19, 12, p. 5529-5540 12 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Multicellular sprouting in vitro

Szabo, A., Mehes, E., Kosa, E. & Czirok, A., Sep 15 2008, In : Biophysical journal. 95, 6, p. 2702-2710 9 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

NMDA receptor NR2B subunit over-expression increases cerebellar granule cell migratory activity

Tárnok, K., Czöndör, K., Jelitai, M., Czirók, A. & Schlett, K., Feb 1 2008, In : Journal of neurochemistry. 104, 3, p. 818-829 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Vascular sprout formation entails tissue deformations and VE-cadherin-dependent cell-autonomous motility

Perryn, E. D., Czirók, A. & Little, C. D., Jan 15 2008, In : Developmental Biology. 313, 2, p. 545-555 11 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)
2007

Network formation of tissue cells via preferential attraction to elongated structures

Szabo, A., Perryn, E. D. & Czirok, A., Jan 26 2007, In : Physical review letters. 98, 3, 038102.

Research output: Contribution to journalArticle

49 Citations (Scopus)

Subventricular zone neuronal progenitors undergo multiple divisions and retract their processes prior to each cytokinesis

Coskun, V., Falls, D. L., Lane, R., Czirok, A. & Luskin, M. B., Aug 1 2007, In : European Journal of Neuroscience. 26, 3, p. 593-604 12 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2006

Elastic fiber formation: A dynamic view of extracellular matrix assembly using timer reporters

Kozel, B. A., Rongish, B. J., Czirok, A., Zach, J., Little, C. D., Davis, E. C., Knutsen, R. H., Wagenseil, J. E., Levy, M. A. & Mecham, R. P., Apr 1 2006, In : Journal of Cellular Physiology. 207, 1, p. 87-96 10 p.

Research output: Contribution to journalArticle

120 Citations (Scopus)

Elastic fiber macro-assembly is a hierarchical, cell motion-mediated process

Czirok, A., Zach, J., Kozel, B. A., Mecham, R. P., Davis, E. C. & Rongish, B. J., Apr 1 2006, In : Journal of Cellular Physiology. 207, 1, p. 97-106 10 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Mesodermal cell displacements during avian gastrulation are due to both individual cell-autonomous and convective tissue movements

Zamir, E. A., Czirók, A., Cui, C., Little, C. D. & Rongish, B. J., Dec 26 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 52, p. 19806-19811 6 p.

Research output: Contribution to journalArticle

84 Citations (Scopus)

New insights into extracellular matrix assembly and reorganization from dynamic imaging of extracellular matrix proteins in living osteoblasts

Sivakumar, P., Czirok, A., Rongish, B. J., Divakara, V. P., Wang, Y. P. & Dallas, S. L., Apr 1 2006, In : Journal of cell science. 119, 7, p. 1350-1360 11 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
2005

A digital image-based method for computational tissue fate mapping during early avian morphogenesis

Zamir, E. A., Czirók, A., Rongish, B. J. & Little, C. D., Jun 1 2005, In : Annals of Biomedical Engineering. 33, 6, p. 854-865 12 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Cerebellar granule cells show age-dependent migratory differences in vitro

Tárnok, K., Czirók, A., Czöndör, K. & Schlett, K., Nov 1 2005, In : Journal of Neurobiology. 65, 2, p. 135-145 11 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Dystroglycan is involved in laminin-1-stimulated motility of Müller glial cells: Combined velocity and directionality analysis

Méhes, E., Czirók, A., Hegedüs, B., Szabó, B., Vicsek, T., Satz, J., Campbell, K. & Jancsik, V., Mar 2005, In : Glia. 49, 4, p. 492-500 9 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Humoral and contact interactions in astroglia/stem cell co-cultures in the course of glia-induced neurogenesis

Környei, Z., Szlávik, V., Szabó, B., Gócza, E., Czirók, A. & Madarász, E., Feb 1 2005, In : Glia. 49, 3, p. 430-444 15 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2004

Auto-reverse nuclear migration in bipolar mammalian cells on micropatterned surfaces

Szabó, B., Környei, Z., Zách, J., Selmeczi, D., Csúcs, G., Czirók, A. & Vicsek, T., Sep 1 2004, In : Cell Motility and the Cytoskeleton. 59, 1, p. 38-49 12 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Extracellular matrix dynamics during vertebrate axis formation

Czirók, A., Rongish, B. J. & Little, C. D., Apr 1 2004, In : Developmental Biology. 268, 1, p. 111-122 12 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

Irradiation and taxol tretment result in non-monotonous dose-dependent changes in the motility of glioblastoma cells

Hegedus, B., Zách, J., Czirók, A., Lövey, J. & Vicsek, T., Mar 1 2004, In : Journal of Neuro-Oncology. 67, 1-2, p. 147-157 11 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)

αvβ3 integrin-dependent endothelial cell dynamics in vivo

Rupp, P. A., Czirók, A. & Little, C. D., Jun 1 2004, In : Development. 131, 12, p. 2887-2897 11 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)
2003

Culturing of avian embryos for time-lapse imaging

Rupp, P. A., Rongish, B. J., Czirok, A. & Little, C. D., Feb 1 2003, In : BioTechniques. 34, 2, p. 274-278 5 p.

Research output: Contribution to journalArticle

Open Access
29 Citations (Scopus)