• 923 Citations
  • 15 h-Index
1991 …2019

Research output per year

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Research Output

2019

Application of human pluripotent stem cells and pluripotent stem cell-derived cellular models for assessing drug toxicity

Apáti, A., Varga, N., Berecz, T., Erdei, Z., Homolya, L. & Sarkadi, B., Jan 2 2019, In : Expert Opinion on Drug Metabolism and Toxicology. 15, 1, p. 61-75 15 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)
2018

Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein

Vőfély, G., Berecz, T., Szabó, E., Szebényi, K., Hathy, E., Orbán, T. I., Sarkadi, B., Homolya, L., Marchetto, M. C., Réthelyi, J. M. & Apáti, Á., Apr 2018, In : Molecular and Cellular Neuroscience. 88, p. 222-230 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells

Erdei, Z., Schamberger, A., Török, G., Szebényi, K., Várady, G., Orbán, T. I., Homolya, L., Sarkadi, B. & Apáti, A., Apr 1 2018, In : PLoS One. 13, 4, e0194925.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2016

Exogenous Nitric Oxide Protects Human Embryonic Stem Cell-Derived Cardiomyocytes against Ischemia/Reperfusion Injury

Pálóczi, J., Varga, Z. V., Apáti, A., Szebényi, K., Sarkadi, B., Madonna, R., De Caterina, R., Csont, T., Eschenhagen, T., Ferdinándy, P. & Görbe, A., 2016, In : Oxidative Medicine and Cellular Longevity. 2016, 4298945.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Functional characterization of the ABCG2 5′ non-coding exon variants: Stem cell specificity, translation efficiency and the influence of drug selection

Sándor, S., Jordanidisz, T., Schamberger, A., Várady, G., Erdei, Z., Apáti, A., Sarkadi, B. & Orbán, T. I., Jul 1 2016, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1859, 7, p. 943-951 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Straightforward and effective synthesis of γ-aminobutyric acid transporter subtype 2-selective acyl-substituted azaspiro[4.5]decanes

Ma, X., Lubin, H., Ioja, E., Kékesi, O., Simon, Á., Apáti, Á., Orbán, T. I., Héja, L., Kardos, J. & Markó, I. E., Jan 15 2016, In : Bioorganic and Medicinal Chemistry Letters. 26, 2, p. 417-423 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

The importance of drug transporters in human pluripotent stem cells and in early tissue differentiation

Apáti, A., Szebényi, K., Erdei, Z., Várady, G., Orbán, T. I. & Sarkadi, B., Jan 2 2016, In : Expert Opinion on Drug Metabolism and Toxicology. 12, 1, p. 77-92 16 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2015

Analysis of intracellular calcium signaling in human embryonic stem cells

Péntek, A., Pászty, K. & Apáti, Á., Jan 1 2015, In : Methods in Molecular Biology. 1307, p. 141-147 7 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Calcium signaling in human pluripotent stem cells

Apáti, A., Berecz, T. & Sarkadi, B., Oct 8 2015, (Accepted/In press) In : Cell Calcium.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Efficient generation of human embryonic stem cell-derived cardiac progenitors based on tissue-specific enhanced green fluorescence protein expression

Szebényi, K., Péntek, A., Erdei, Z., Várady, G., Orbán, T. I., Sarkadi, B. & Apáti, Á., Jan 1 2015, In : Tissue Engineering - Part C: Methods. 21, 1, p. 35-45 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Expression of Tight Junction Components in Hepatocyte-Like Cells Differentiated from Human Embryonic Stem Cells

Erdélyi-Belle, B., Török, G., Apáti, Á., Sarkadi, B., Schaff, Z., Kiss, A. & Homolya, L., Sep 28 2015, In : Pathology and Oncology Research. 21, 4, p. 1059-1070 12 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Generation of a Homozygous Transgenic Rat Strain Stably Expressing a Calcium Sensor Protein for Direct Examination of Calcium Signaling

Szebenyi, K., Füredi, A., Kolacsek, O., Pergel, E., Bosze, Z., Bender, B., Vajdovich, P., Tovari, J., Homolya, L., Szakacs, G., Heja, L., Enyedi, A., Sarkadi, B., Apati, A. & Orban, T. I., Aug 3 2015, In : Scientific reports. 5, 12645.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Mesenchymal Stromal Cell-Like Cells Set the Balance of Stimulatory and Inhibitory Signals in Monocyte-Derived Dendritic Cells

Bacskai, I., Mázló, A., Kis-Tóth, K., Szabó, A., Panyi, G., Sarkadi, B., Apáti, Á. & Rajnavölgyi, É., Aug 1 2015, In : Stem Cells and Development. 24, 15, p. 1805-1816 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Visualization of calcium dynamics in kidney proximal tubules

Szebényi, K., Füredi, A., Kolacsek, O., Csohány, R., Prókai, Á., Kis-Petik, K., Szabó, A., Bosze, Z., Bender, B., Tóvári, J., Enyedi, Á., Orbán, T. I., Apáti, Á. & Sarkadi, B., Nov 2015, In : Journal of the American Society of Nephrology. 26, 11, p. 2731-2740 10 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2014

Excision efficiency is not strongly coupled to transgenic rate: Cell type-dependent transposition efficiency of sleeping beauty and piggy bac DNA transposons

Kolacsek, O., Erdei, Z., Apáti, Á., Sándor, S., Izsvák, Z., Ivics, Z., Sarkadi, B. & Orbán, T. I., Aug 1 2014, In : Human Gene Therapy Methods. 25, 4, p. 241-252 12 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Expression pattern of the human ABC transporters in pluripotent embryonic stem cells and in their derivatives

Erdei, Z., Lorincz, R., Szebényi, K., Péntek, A., Varga, N., Likó, I., Várady, G., Szakács, G., Orbán, T. I., Sarkadi, B. & Apáti, Á., Sep 2014, In : Cytometry Part B - Clinical Cytometry. 86, 5, p. 299-310 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Human Stem-Cell-Derived Cardiomyocytes in Drug Discovery and Toxicity Testing

Szebényi, K., Péntek, A., Varga, N., Erdei, Z., Vofély, G., Orbán, T. I., Sarkadi, B. & Apáti, Á., Jun 3 2014, Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology. Wiley Blackwell, p. 267-298 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

Characterization of calcium signals in human embryonic stem cells and in their differentiated offspring by a stably integrated calcium indicator protein

Apáti, Á., Pászty, K., Hegedus, L., Kolacsek, O., Orbán, T. I., Erdei, Z., Szebényi, K., Péntek, A., Enyedi, Á. & Sarkadi, B., Apr 1 2013, In : Cellular Signalling. 25, 4, p. 752-759 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Dynamic ABCG2 expression in human embryonic stem cells provides the basis for stress response

Erdei, Z., Sarkadi, B., Brózik, A., Szebényi, K., Várady, G., Makó, V., Péntek, A., Orbán, T. I. & Apáti, Á., Mar 1 2013, In : European Biophysics Journal. 42, 2-3, p. 169-179 11 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Erratum: Reliable transgene-independent method for determining sleeping beauty transposon copy numbers (Mobile DNA 4 (11))

Kolacsek, O., Krízsik, V., Schamberger, A., Erdei, Z., Apáti, Á., Várady, G., Mátés, L., Izsvák, Z., Ivics, Z., Sarkadi, B. & Orbán, T. I., Mar 25 2013, In : Mobile DNA. 4, 1, 11.

Research output: Contribution to journalComment/debate

2 Citations (Scopus)

Modulation of endoplasmic reticulum calcium pump expression during lung cancer cell differentiation

Arbabian, A., Brouland, J. P., Apáti, Á., Pászty, K., Hegedus, L., Enyedi, Á., Chomienne, C. & Papp, B., Nov 1 2013, In : FEBS Journal. 280, 21, p. 5408-5418 11 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
2012

Calcium signaling in pluripotent stem cells

Apáti, Á., Pászty, K., Erdei, Z., Szebényi, K., Homolya, L. & Sarkadi, B., Apr 28 2012, In : Molecular and Cellular Endocrinology. 353, 1-2, p. 57-67 11 p.

Research output: Contribution to journalReview article

23 Citations (Scopus)

Endoplasmic reticulum calcium pumps and cancer cell differentiation

Papp, B., Brouland, J. P., Arbabian, A., Gélébart, P., Kovács, T., Bobe, R., Enouf, J., Varin-Blank, N. & Apáti, Á., Mar 2012, In : Biomolecules. 2, 1, p. 165-186 22 p.

Research output: Contribution to journalReview article

29 Citations (Scopus)
2011

Human pluripotent stem cells in pharmacological and toxicological screening: New perspectives for personalized medicine

Szebényi, K., Erdei, Z., Péntek, A., Sebe, A., Orbán, T. I., Sarkadi, B. & Apáti, Á., May 1 2011, In : Personalized Medicine. 8, 3, p. 347-364 18 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)
17 Citations (Scopus)

Reliable transgene-independent method for determining Sleeping Beauty transposon copy numbers

Kolacsek, O., Krízsik, V., Schamberger, A., Erdei, Z., Apáti, Á., Várady, G., Mátés, L., Izsvák, Z., Ivics, Z., Sarkadi, B. & Orbán, T. I., Dec 1 2011, In : Mobile DNA. 2, 1, 5.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2010

A novel synthetic adhesive peptide conjugate supports the xeno-free culturing of embryonic and neural stem cells

Markó, K., Gócza, E., Apáti, Á., Köhidi, T. & Madarász, E., Nov 2010, In : European Cells and Materials. 20, SUPPL.3, 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Evaluation of ABCG2 expression in human embryonic stem cells: Crossing the same river twice?

Sarkadi, B., Orbán, T. I., Szakács, G., Várady, G., Schamberger, A., Erdei, Z., Szebényi, K., Homolya, L. & Apáti, Á., Jan 1 2010, In : Stem Cells. 28, 1, p. 174-176 3 p.

Research output: Contribution to journalLetter

24 Citations (Scopus)
2009

Applying a "double-feature" promoter to identify cardiomyocytes differentiated from human embryonic stem cells following transposon-based gene delivery

Orbán, T. I., Apáti, Á., Németh, A., Varga, N., Krizsik, V., Schamberger, A., Szebényi, K., Erdei, Z., Várady, G., Karászi, É., Homolya, L., Német, K., Gócza, E., Miskey, C., Mátés, L., Ivics, Z., Izsvák, Z. & Sarkadi, B., May 1 2009, In : Stem Cells. 27, 5, p. 1077-1087 11 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
152 Citations (Scopus)
2008

All-trans-retinoic acid enhances apoptosis induction by tyrosine kinase inhibitors in the eosinophilic leukemia-derived EoL-1 cell line

Robert, C., Apàti, À., Chomienne, C. & Papp, B., Feb 1 2008, In : Leukemia Research. 32, 2, p. 343-346 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

High level functional expression of the ABCG2 multidrug transporter in undifferentiated human embryonic stem cells

Apáti, Á., Orbán, T. I., Varga, N., Németh, A., Schamberger, A., Krizsik, V., Erdélyi-Belle, B., Homolya, L., Várady, G., Padányi, R., Karászi, É., Kemna, E. W. M., Német, K. & Sarkadi, B., Dec 1 2008, In : Biochimica et Biophysica Acta - Biomembranes. 1778, 12, p. 2700-2709 10 p.

Research output: Contribution to journalArticle

64 Citations (Scopus)
2005
191 Citations (Scopus)
2004

Calpain as a multi-site regulator of cell cycle

Jánossy, J., Ubezio, P., Apáti, Á., Magócsi, M., Tompa, P. & Friedrich, P., Apr 15 2004, In : Biochemical Pharmacology. 67, 8, p. 1513-1521 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)
2003
50 Citations (Scopus)
13 Citations (Scopus)
2001

Activation of Raf/ERK1/2 MAP kinase pathway is involved in GM-CSF-induced proliferation and survival but not in erythropoietin-induced differentiation of TF-1 cells

Kolonics, A., Apáti, Á., Jánossy, J., Brózik, A., Gáti, R., Schaefer, A. & Magócsi, M., Sep 11 2001, In : Cellular Signalling. 13, 10, p. 743-754 12 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

Unregulated activation of STAT-5, ERK1/2 and c-Fos may contribute to the phenotypic transformation from myelodysplastic syndrome to acute leukaemia

Kolonics, A., Apáti, Á., Nahajevszky, S., Gáti, R., Brózik, A. & Magócsi, M., Dec 29 2001, In : Haematologia. 31, 2, p. 125-138 14 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
1999

Signalling mechanisms and the role of calcineurin in erythropoiesis

Magócsi, M., Apáti, Á., Gáti, R. & Kolonics, A., May 3 1999, In : Immunology letters. 68, 1, p. 187-195 9 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
1993

Oncogene expression in thymocytes after emetine treatment of mice

Schweighoffer, T., Schweighoffer, E., Sviresheva, M., Apati, A., Balogh, A., Csuka, I., Luat, N. N. & Banfalvi, G., Dec 1 1993, In : Cellular and Molecular Biology Research. 39, 7, p. 647-656 10 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
1991

Cytometric analysis of DNA replication inhibited by emetime and cyclosporin A

Schweighoffer, T., Schweighoffer, E., Apati, A., Antoni, F., Molnar, G., Lapis, K. & Banfalvi, G., May 1 1991, In : Histochemistry. 96, 1, p. 93-97 5 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)