• 2141 Citations
  • 15 h-Index
20012020

Research output per year

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Research Output

  • 2141 Citations
  • 15 h-Index
  • 32 Article
  • 1 Chapter
  • 1 Review article
2020

Exclusive neuronal detection of KGDHC-specific subunits in the adult human brain cortex despite pancellular protein lysine succinylation

Dobolyi, A., Bago, A., Palkovits, M., Nemeria, N. S., Jordan, F., Doczi, J., Ambrus, A., Adam-Vizi, V. & Chinopoulos, C., Mar 1 2020, In : Brain Structure and Function. 225, 2, p. 639-667 29 p.

Research output: Contribution to journalArticle

Open Access
2019
Open Access

Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants

Szabo, E., Wilk, P., Nagy, B., Zambo, Z., Bui, D., Weichsel, A., Arjunan, P., Torocsik, B., Hubert, A., Furey, W., Montfort, W. R., Jordan, F., Weiss, M. S., Adam-Vizi, V. & Ambrus, A., Oct 15 2019, In : Human molecular genetics. 28, 20, p. 3339-3354 16 p.

Research output: Contribution to journalArticle

2018

A multipronged approach unravels unprecedented protein–protein interactions in the human 2-oxoglutarate dehydrogenase multienzyme complex

Zhou, J., Yang, L., Ozohanics, O., Zhang, X., Wang, J., Ambrus, A., Arjunan, P., Brukh, R., Nemeria, N. S., Furey, W. & Jordan, F., Jan 1 2018, In : Journal of Biological Chemistry. 293, 50, p. 19213-19227 15 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase

Szabo, E., Mizsei, R., Wilk, P., Zambo, Z., Torocsik, B., Weiss, M. S., Adam-Vizi, V. & Ambrus, A., Aug 20 2018, In : Free Radical Biology and Medicine. 124, p. 214-220 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

DNA binding of sunitinib: Spectroscopic evidence via circular dichroism and nuclear magnetic resonance

Kiss, E., Mirzahosseini, A., Hubert, Á., Ambrus, A., Őrfi, L. & Horváth, P., Feb 20 2018, In : Journal of Pharmaceutical and Biomedical Analysis. 150, p. 355-361 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
8 Citations (Scopus)

Membrane potential and delta pH dependency of reverse electron transport-associated hydrogen peroxide production in brain and heart mitochondria

Komlódi, T., Geibl, F. F., Sassani, M., Ambrus, A. & Tretter, L., Oct 1 2018, In : Journal of Bioenergetics and Biomembranes. 50, 5, p. 355-365 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I

Mikulás, K., Hermann, P., Gera, I., Komlódi, T., Horváth, G., Ambrus, A. & Tretter, L., Jul 2018, In : Dental Materials. 34, 7, p. e166-e181

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016
9 Citations (Scopus)
2015
25 Citations (Scopus)
6 Citations (Scopus)
2014

Human 2-oxoglutarate dehydrogenase complex E1 component forms a thiamin-derived radical by aerobic oxidation of the enamine intermediate

Nemeria, N. S., Ambrus, A., Patel, H., Gerfen, G., Adam-Vizi, V., Tretter, L., Zhou, J., Wang, J. & Jordan, F., Oct 24 2014, In : Journal of Biological Chemistry. 289, 43, p. 29859-29873 15 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Measurement of ROS homeostasis in isolated mitochondria

Tretter, L. & Ambrus, A., 2014, Methods in Enzymology. C ed. Academic Press Inc., p. 199-223 25 p. (Methods in Enzymology; vol. 547, no. C).

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Citations (Scopus)
2013
16 Citations (Scopus)
2011

Stimulation of reactive oxygen species generation by disease-causing mutations of lipoamide dehydrogenase

Ambrus, A., Torocsik, B., Tretter, L., Ozohanics, O. & Adam-Vizi, V., Aug 1 2011, In : Human molecular genetics. 20, 15, p. 2984-2995 12 p., ddr202.

Research output: Contribution to journalArticle

28 Citations (Scopus)
2009

A direct and nondestructive approach to determine the folding structure of the I-motif DNA secondary structure by NMR

Dai, J., Ambrus, A., Hurley, L. H. & Yang, D., May 6 2009, In : Journal of the American Chemical Society. 131, 17, p. 6102-6104 3 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

A re-evaluation of the role of matrix acidification in uncoupler-induced Ca2+ release from mitochondria

Vajda, S., Mándi, M., Konràd, C., Kiss, G., Ambrus, A., Adam-Vizi, V. & Chinopoulos, C., May 1 2009, In : FEBS Journal. 276, 10, p. 2713-2724 12 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)
37 Citations (Scopus)
13 Citations (Scopus)

Refolding of the human dihydrolipoamide dehydrogenase

Ambrus, A., Torocsik, B. & Adam-Vizi, V., Jul 15 2009, In : Biochemical Engineering Journal. 45, 2, p. 120-125 6 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2007

Diffusion-ordered nuclear magnetic resonance spectroscopy for analysis of DNA secondary structural elements

Ambrus, A. & Yang, D., Aug 1 2007, In : Analytical Biochemistry. 367, 1, p. 56-67 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

Structure of the intramolecular human telomeric G-quadruplex in potassium solution: A novel adenine triple formation

Dai, J., Punchihewa, C., Ambrus, A., Chen, D., Jones, R. A. & Yang, D., Apr 1 2007, In : Nucleic acids research. 35, 7, p. 2440-2450 11 p.

Research output: Contribution to journalArticle

244 Citations (Scopus)
2006

An intramolecular G-quadruplex structure with mixed parallel/antiparallel G-strands formed in the human BCL-2 promoter region in solution

Dai, J., Dexheimer, T. S., Chen, D., Carver, M., Ambrus, A., Jones, R. A. & Yang, D., Feb 1 2006, In : Journal of the American Chemical Society. 128, 4, p. 1096-1098 3 p.

Research output: Contribution to journalArticle

297 Citations (Scopus)

Human telomeric sequence forms a hybrid-type intramolecular G-quadruplex structure with mixed parallel/antiparallel strands in potassium solution

Ambrus, A., Chen, D., Dai, J., Bialis, T., Jones, R. A. & Yang, D., Jul 10 2006, In : Nucleic acids research. 34, 9, p. 2723-2735 13 p.

Research output: Contribution to journalArticle

768 Citations (Scopus)

Oligomerization of nitrophorins

Ambrus, A., Friedrich, K. & Somogyi, Á., May 15 2006, In : Analytical Biochemistry. 352, 2, p. 286-295 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2005

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry protocol for monitoring the progress of enzymatic 13C/15N-labeled DNA syntheses

Ambrus, A., Chen, D., Whatcott, C., Somogyi, Á. & Yang, D., Jul 15 2005, In : Analytical Biochemistry. 342, 2, p. 246-253 8 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Solution structure of the biologically relevant G-quadruplex element in the human c-MYC promoter. Implications for G-quadruplex stabilization

Ambrus, A., Chen, D., Dai, J., Jones, R. A. & Yang, D., Feb 15 2005, In : Biochemistry. 44, 6, p. 2048-2058 11 p.

Research output: Contribution to journalArticle

356 Citations (Scopus)

Total and semisynthesis and in vitro studies of both enantiomers of 20-fluorocamptothecin

Tangirala, R. S., Dixon, R., Yang, D., Ambrus, A., Antony, S., Agama, K., Pommier, Y. & Curran, D. P., Nov 1 2005, In : Bioorganic and Medicinal Chemistry Letters. 15, 21, p. 4736-4740 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2003

A labile regulatory copper ion lies near the T1 copper site in the multicopper oxidase CueO

Roberts, S. A., Wildner, G. F., Grass, G., Weichsel, A., Ambrus, A., Rensing, C. & Montfort, W. R., Aug 22 2003, In : Journal of Biological Chemistry. 278, 34, p. 31958-31963 6 p.

Research output: Contribution to journalArticle

114 Citations (Scopus)
2001

Calcium binding of transglutaminases: A 43Ca NMR study combined with surface polarity analysis

Ambrusa, A., Bányaib, I., Weissc, M. S., Hilgenfeldc, R., Keresztessya, Z., Muszbekd, L. & Fésüsa, L., Jan 1 2001, In : Journal of Biomolecular Structure and Dynamics. 19, 1, p. 59-74 16 p.

Research output: Contribution to journalArticle

27 Citations (Scopus)
7 Citations (Scopus)

Structural and biochemical characterization of neuronal calretinin domain I-II (residues 1-100): Comparison to homologous calbindin D28k domain I-II (residues 1-93)

Palczewska, M., Groves, P., Ambrus, A., Kaleta, A., Kövér, K. E., Batta, G. & Kuznicki, J., Dec 22 2001, In : European Journal of Biochemistry. 268, 23, p. 6229-6237 9 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)